Store-operated calcium channels
M Prakriya, RS Lewis - Physiological reviews, 2015 - journals.physiology.org
Store-operated calcium channels (SOCs) are a major pathway for calcium signaling in
virtually all metozoan cells and serve a wide variety of functions ranging from gene …
virtually all metozoan cells and serve a wide variety of functions ranging from gene …
STIMulating store-operated Ca2+ entry
MD Cahalan - Nature cell biology, 2009 - nature.com
Calcium influx through plasma membrane store-operated Ca2+ (SOC) channels is triggered
when the endoplasmic reticulum (ER) Ca2+ store is depleted—a homeostatic Ca2+ …
when the endoplasmic reticulum (ER) Ca2+ store is depleted—a homeostatic Ca2+ …
[HTML][HTML] Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry
Summary Stromal interaction molecule-1 (STIM1) activates store-operated Ca 2+ entry
(SOCE) in response to diminished luminal Ca 2+ levels. Here, we present the atomic …
(SOCE) in response to diminished luminal Ca 2+ levels. Here, we present the atomic …
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling
E Brailoiu, D Churamani, X Cai, MG Schrlau… - Journal of Cell …, 2009 - rupress.org
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a widespread and potent calcium-
mobilizing messenger that is highly unusual in activating calcium channels located on acidic …
mobilizing messenger that is highly unusual in activating calcium channels located on acidic …
Molecular mechanisms of STIM/Orai communication
Ca2+ entry into the cell via store-operated Ca2+ release-activated Ca2+ (CRAC) channels
triggers diverse signaling cascades that affect cellular processes like cell growth, gene …
triggers diverse signaling cascades that affect cellular processes like cell growth, gene …
Oocyte activation deficiency and assisted oocyte activation: mechanisms, obstacles and prospects for clinical application
BACKGROUND Oocyte activation deficiency (OAD) is attributed to the majority of cases
underlying failure of ICSI cycles, the standard treatment for male factor infertility. Oocyte …
underlying failure of ICSI cycles, the standard treatment for male factor infertility. Oocyte …
Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kinetics
PB Stathopulos, L Zheng, M Ikura - Journal of Biological Chemistry, 2009 - ASBMB
Stromal interaction molecules (STIM) 1 and STIM2 are regulators of store-operated calcium
(Ca 2+) entry as well as basal cytoplasmic Ca 2+ levels in human cells. Despite a high …
(Ca 2+) entry as well as basal cytoplasmic Ca 2+ levels in human cells. Despite a high …
Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2
L Zheng, PB Stathopulos, GY Li, M Ikura - Biochemical and biophysical …, 2008 - Elsevier
Stromal interaction molecule 1 (STIM1) is an endoplasmic reticulum (ER)-membrane
associated Ca2+ sensor which activates store-operated Ca2+ entry (SOCE). Its homologue …
associated Ca2+ sensor which activates store-operated Ca2+ entry (SOCE). Its homologue …
Light generation of intracellular Ca2+ signals by a genetically encoded protein BACCS
Ca2+ signals are highly regulated in a spatiotemporal manner in numerous cellular
physiological events. Here we report a genetically engineered blue light-activated Ca2+ …
physiological events. Here we report a genetically engineered blue light-activated Ca2+ …
Role of STIM2 in cell function and physiopathology
A Berna‐Erro, I Jardin, GM Salido… - The Journal of …, 2017 - Wiley Online Library
An endoplasmic reticulum (ER)‐resident protein that regulates cytosolic and ER free‐Ca2+
concentration by induction of store‐operated calcium entry: that is the original definition of …
concentration by induction of store‐operated calcium entry: that is the original definition of …