2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease: a report of the …
Writing Group Members, LF Hiratzka, GL Bakris… - Circulation, 2010 - Am Heart Assoc
2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the Diagnosis and
Management of Patients With Thoracic Aortic Disease | Circulation Science Volunteer Warning …
Management of Patients With Thoracic Aortic Disease | Circulation Science Volunteer Warning …
Acute aortic dissection
J Golledge, KA Eagle - The Lancet, 2008 - thelancet.com
We summarise advances in the epidemiology, presentation, pathogenesis, diagnosis, and
management of acute aortic dissection. Improved understanding of this problem has been …
management of acute aortic dissection. Improved understanding of this problem has been …
Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus
L Zhu, R Vranckx, PK Van Kien, A Lalande, N Boisset… - Nature …, 2006 - nature.com
We have recently described two kindreds presenting thoracic aortic aneurysm and/or aortic
dissection (TAAD) and patent ductus arteriosus (PDA), and mapped the disease locus to …
dissection (TAAD) and patent ductus arteriosus (PDA), and mapped the disease locus to …
Cellular and molecular mechanisms of thoracic aortic aneurysms
I El-Hamamsy, MH Yacoub - Nature Reviews Cardiology, 2009 - nature.com
Thoracic aortic aneurysms (TAA) increase the risk of aortic dissection or rupture and
represent an important source of morbidity and mortality. Inherited forms of the disease …
represent an important source of morbidity and mortality. Inherited forms of the disease …
Genetic basis of thoracic aortic aneurysms and dissections: focus on smooth muscle cell contractile dysfunction
DM Milewicz, DC Guo, V Tran-Fadulu… - … Rev. Genomics Hum …, 2008 - annualreviews.org
Thoracic aortic aneurysms leading to type A dissections (TAAD) can be inherited in isolation
or in association with genetic syndromes, such as Marfan syndrome and Loeys-Dietz …
or in association with genetic syndromes, such as Marfan syndrome and Loeys-Dietz …
Between Rho (k) and a hard place: the relation between vessel wall stiffness, endothelial contractility, and cardiovascular disease
S Huveneers, MJAP Daemen, PL Hordijk - Circulation research, 2015 - Am Heart Assoc
Vascular stiffness is a mechanical property of the vessel wall that affects blood pressure,
permeability, and inflammation. As a result, vascular stiffness is a key driver of (chronic) …
permeability, and inflammation. As a result, vascular stiffness is a key driver of (chronic) …
Guidelines for Diagnosis and Treatment of Aortic Aneurysm and Aortic Dissection (JCS 2011)–Digest Version–
JCS Joint Working Group - Circulation Journal, 2013 - jstage.jst.go.jp
Thoracic stent-grafts provided by manufacturers were approved in Japan in March 2008,
and their use is now spreading rapidly. Evidence of the efficacy of this treatment in TAA is …
and their use is now spreading rapidly. Evidence of the efficacy of this treatment in TAA is …
MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II
H Pannu, V Tran-Fadulu, CL Papke… - Human molecular …, 2007 - academic.oup.com
Non-syndromic thoracic aortic aneurysms and dissections (TAADs) are inherited in an
autosomal dominant manner in∼ 20% of cases. Familial TAAD is genetically …
autosomal dominant manner in∼ 20% of cases. Familial TAAD is genetically …
Genetics of thoracic aortic aneurysm: at the crossroad of transforming growth factor-β signaling and vascular smooth muscle cell contractility
E Gillis, L Van Laer, BL Loeys - Circulation research, 2013 - Am Heart Assoc
Aortic aneurysm, including both abdominal aortic aneurysm and thoracic aortic aneurysm, is
the cause of death of 1% to 2% of the Western population. This review focuses only on …
the cause of death of 1% to 2% of the Western population. This review focuses only on …
Aortic aneurysms: an immune disease with a strong genetic component
noted that the patients did not fit the diagnostic criteria of Marfan syndrome. Many reports
have been published since then, and systematic studies have established that 20% of …
have been published since then, and systematic studies have established that 20% of …