Cancer is a class of diseases characterized by uncontrolled cell growth and has the ability to
spread or metastasize throughout the body. In recent years, remarkable progress has been …

The current concept of radiobiology posits that damage to the DNA in the cell nucleus is the
primary cause for the detrimental effects of radiation. However, emerging experimental …

Research on radiation carcinogenesis during the past 2 decades has focused on cellular
and molecular mechanisms for the effects of radiation in mammalian cells. This paper will …

It has generally been considered that important biological effects of ionizing radiation arise
as a direct consequence of DNA damage occurring in irradiated cells. We have examined …

The term radiation-induced bystander effects describes a situation where cells that have not
been directly exposed to ionizing radiation behave as though they have been exposed: they …

Morgan, W. Non-targeted and Delayed Effects of Exposure to Ionizing Radiation: I. Radiation-
Induced Genomic Instability and Bystander Effects In Vitro. Radiat. Res. 159, 567–580 …

We demonstrate by western analysis that the expression levels of TP53 (formerly known as
p53), CDKN1A (formerly known as), CDC2 (formerly known as), CCNB1 (cyclin B1) and …

Abstract Mothersill, C. and Seymour, C. Radiation-Induced Bystander Effects: Past History
and Future Directions. Radiat. Res. 155, 757–765 (2001). There has been a recent upsurge …

Ever since the discovery of X-rays was made by Röntgen more than a hundred years ago, it
has always been accepted that the deleterious effects of ionizing radiation such as mutation …

Ever since x-rays were shown to induce mutation in Drosophila more than 70 years ago,
prevailing dogma considered the genotoxic effects of ionizing radiation, such as mutations …