Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Peroxisomes are dynamic organelles that play an essential role in a variety of cellular
catabolic and anabolic metabolic pathways, including fatty acid alpha-and beta-oxidation …

Current approaches for the production of high-value compounds in microorganisms mostly
use the cytosol as a general reaction vessel. However, competing pathways and metabolic …

Peroxisome biogenesis disorders in the Zellweger spectrum (PBD-ZSD) are a
heterogeneous group of genetic disorders caused by mutations in PEX genes responsible …

Sensing viruses by pattern recognition receptors (PRR) triggers the innate immune system
of the host cell and activates immune signaling cascades such as the RIG-I/IRF3 pathway …

Peroxisomes are unique among the organelles of the endomembrane system. Unlike other
organelles that derive most if not all of their proteins from the ER (endoplasmic reticulum) …

Understanding organelle biogenesis is a central focus of cell biology. Whereas some are
generated from existing organelles, others can be generated de novo. Most de novo …

Peroxisomes are conserved organelles of eukaryotic cells with important roles in cellular
metabolism, human health, redox homeostasis, as well as intracellular metabolite transfer …

Peroxisomes proliferate by growth and division of pre-existing peroxisomes or could arise
de novo. Though the de novo pathway of peroxisome biogenesis is a more recent discovery …

Tools to image membrane tension in response to mechanical stimuli are badly needed in
mechanobiology. We have recently introduced mechanosensitive flipper probes to report …