Smoking is a serious global health issue. Cigarette smoking contains over 7000 different
chemicals. The main harmful components include nicotine, acrolein, aromatic hydrocarbons …

The immune system is regulated by distinct signaling pathways that control the development
and function of the immune cells. Accumulating evidence suggest that ligation of aryl …

Since its first release in 2007, GeneCodis has become a valuable tool to functionally
interpret results from experimental techniques in genomics. This web-based application …

DNA methylation is important for gene regulation and is vulnerable to early-life exposure to
environmental contaminants. We found that direct waterborne benzo [a] pyrene (BaP) …

Rationale: Chronic obstructive pulmonary disease (COPD) is associated with lung fibroblast
senescence, a process characterized by the irreversible loss of replicative capacity …

This study aimed to compare the aerosol chemistry and in vitro toxicological profiles of two
prototype Heated Tobacco Product (p-HTP) variants to the 1R6F Reference Cigarette. In the …

Tobacco kills nearly 6 million people each year, and 90% of the annual 1.59 million lung
cancer deaths worldwide are caused by cigarette smoke. Clinically, a long latency is …

The interest in phytochemicals found in plant foods as bioactive components of the diet has
expanded in the last few years. This is because they have been linked with the prevention or …

More than 90% of lung cancers are caused by cigarette smoke and air pollution, with
polycyclic aromatic hydrocarbons (PAHs) as key carcinogens. In Xuanwei City of Yunnan …

Benzo [a] pyrene (BaP), a polycyclic aromatic hydrocarbon in the air, triggers pulmonary
inflammation. This study focused on BaP-induced inflammation in the alveolar epithelium …