Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies
K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …
personalized medicine. This review covers the principles, advantages, and drawbacks of …
Nanomedicine (s) under the microscope
R Duncan, R Gaspar - Molecular pharmaceutics, 2011 - ACS Publications
Depending on the context, nanotechnologies developed as nanomedicines (nanosized
therapeutics and imaging agents) are presented as either a remarkable technological …
therapeutics and imaging agents) are presented as either a remarkable technological …
Polymers for drug delivery systems
WB Liechty, DR Kryscio, BV Slaughter… - Annual review of …, 2010 - annualreviews.org
Polymers have played an integral role in the advancement of drug delivery technology by
providing controlled release of therapeutic agents in constant doses over long periods …
providing controlled release of therapeutic agents in constant doses over long periods …
The dawning era of polymer therapeutics
R Duncan - Nature reviews Drug discovery, 2003 - nature.com
As we enter the twenty-first century, research at the interface of polymer chemistry and the
biomedical sciences has given rise to the first nano-sized (5–100 nm) polymer-based …
biomedical sciences has given rise to the first nano-sized (5–100 nm) polymer-based …
Biodegradable polymers
R Chandra, R Rustgi - Progress in polymer science, 1998 - Elsevier
Biodegradable polymers are a newly emerging field. A vast number of biodegradable
polymers have been synthesized recently and some microorganisms and enzymes capable …
polymers have been synthesized recently and some microorganisms and enzymes capable …
The chemistry and applications of antimicrobial polymers: a state-of-the-art review
ER Kenawy, SD Worley, R Broughton - Biomacromolecules, 2007 - ACS Publications
Microbial infection remains one of the most serious complications in several areas,
particularly in medical devices, drugs, health care and hygienic applications, water …
particularly in medical devices, drugs, health care and hygienic applications, water …
Poly (amidoamine)(PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications
R Esfand, DA Tomalia - Drug discovery today, 2001 - Elsevier
Poly (amidoamine)(PAMAM) dendrimers are the first complete dendrimer family to be
synthesized, characterized and commercialized. Based on this extensive activity, they are …
synthesized, characterized and commercialized. Based on this extensive activity, they are …
Noncovalent interactions: a challenge for experiment and theory
K Müller-Dethlefs, P Hobza - Chemical Reviews, 2000 - ACS Publications
A common phenomenon resulting from the interaction of atoms is the formation of
molecules, under certain conditions. This well-known type of interaction is termed covalent …
molecules, under certain conditions. This well-known type of interaction is termed covalent …
Polymer therapeutics-prospects for 21st century: the end of the beginning
R Duncan, MJ Vicent - Advanced drug delivery reviews, 2013 - Elsevier
The term “polymer therapeutics” was coined to describe polymeric drugs, polymer
conjugates of proteins, drugs and aptamers, together with those block copolymer micelles …
conjugates of proteins, drugs and aptamers, together with those block copolymer micelles …
Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture
ME Fox, FC Szoka, JMJ Fréchet - Accounts of chemical research, 2009 - ACS Publications
Chemotherapy can destroy tumors and arrest cancer progress. Unfortunately, severe side
effects (treatment is usually a series of injections of highly toxic drugs) often restrict the …
effects (treatment is usually a series of injections of highly toxic drugs) often restrict the …