[HTML][HTML] Multi-omics approaches in cancer research with applications in tumor subtyping, prognosis, and diagnosis
O Menyhárt, B Győrffy - Computational and structural biotechnology journal, 2021 - Elsevier
While cost-effective high-throughput technologies provide an increasing amount of data, the
analyses of single layers of data seldom provide causal relations. Multi-omics data …
analyses of single layers of data seldom provide causal relations. Multi-omics data …
Onco‐multi‐OMICS approach: a new frontier in cancer research
The acquisition of cancer hallmarks requires molecular alterations at multiple levels
including genome, epigenome, transcriptome, proteome, and metabolome. In the past …
including genome, epigenome, transcriptome, proteome, and metabolome. In the past …
Pediatrics consequences of caesarean section—a systematic review and meta-analysis
A Słabuszewska-Jóźwiak, JK Szymański… - International journal of …, 2020 - mdpi.com
Background: Cesarean section is a surgical procedure, which is the most frequently
performed in gynecology and obstetrics. It is commonly believed that an operative delivery is …
performed in gynecology and obstetrics. It is commonly believed that an operative delivery is …
DNA methylation: conducting the orchestra from exposure to phenotype?
FAD Leenen, CP Muller, JD Turner - Clinical epigenetics, 2016 - Springer
Abstract DNA methylation, through 5-methyl-and 5-hydroxymethylcytosine (5mC and 5hmC),
is considered to be one of the principal interfaces between the genome and our …
is considered to be one of the principal interfaces between the genome and our …
Accelerated placental aging in early onset preeclampsia pregnancies identified by DNA methylation
Aim: To determine whether dynamic DNA methylation changes in the human placenta can
be used to predict gestational age. Materials & methods: Publicly available placental DNA …
be used to predict gestational age. Materials & methods: Publicly available placental DNA …
Artificial intelligence to decode cancer mechanism: beyond patient stratification for precision oncology
The multitude of multi-omics data generated cost-effectively using advanced high-
throughput technologies has imposed challenging domain for research in Artificial …
throughput technologies has imposed challenging domain for research in Artificial …
Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers
Although promoter-associated CpG islands have been established as targets of DNA
methylation changes in cancer, previous studies suggest that epigenetic dysregulation …
methylation changes in cancer, previous studies suggest that epigenetic dysregulation …
UHRF1: The key regulator of epigenetics and molecular target for cancer therapeutics
H Sidhu, N Capalash - Tumor biology, 2017 - journals.sagepub.com
UHRF1 is a master regulator of epigenome as it coordinates DNA methylation and histone
modifications. Compelling evidence suggests a strong link between UHRF1 overexpression …
modifications. Compelling evidence suggests a strong link between UHRF1 overexpression …
Distinct chromatin signatures of DNA hypomethylation in aging and cancer
Cancer is an aging‐associated disease, but the underlying molecular links between these
processes are still largely unknown. Gene promoters that become hypermethylated in aging …
processes are still largely unknown. Gene promoters that become hypermethylated in aging …
The Network Zoo: a multilingual package for the inference and analysis of gene regulatory networks
Inference and analysis of gene regulatory networks (GRNs) require software that integrates
multi-omic data from various sources. The Network Zoo (netZoo; netzoo. github. io) is a …
multi-omic data from various sources. The Network Zoo (netZoo; netzoo. github. io) is a …