The role of Epstein-Barr virus in multiple sclerosis: from molecular pathophysiology to: in vivo: imaging
Multiple sclerosis (MS) is a disease of the central nervous system characterized by
inflammation, demyelination, and neuronal damage. Environmental and genetic factors are …
inflammation, demyelination, and neuronal damage. Environmental and genetic factors are …
Epstein-Barr virus (EBV) reactivation and therapeutic inhibitors
JR Kerr - Journal of clinical pathology, 2019 - jcp.bmj.com
Epstein-Barr virus (EBV) is a ubiquitous human virus which infects almost all humans during
their lifetime and following the acute phase, persists for the remainder of the life of the …
their lifetime and following the acute phase, persists for the remainder of the life of the …
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients
T-cell immunotherapy that takes advantage of Epstein-Barr virus (EBV)–stimulated immunity
has the potential to fill an important niche in targeted therapy for EBV-related cancers. To …
has the potential to fill an important niche in targeted therapy for EBV-related cancers. To …
Lymph node targeted multi-epitope subunit vaccine promotes effective immunity to EBV in HLA-expressing mice
V Dasari, LK McNeil, K Beckett, M Solomon… - Nature …, 2023 - nature.com
The recent emergence of a causal link between Epstein-Barr virus (EBV) and multiple
sclerosis has generated considerable interest in the development of an effective vaccine …
sclerosis has generated considerable interest in the development of an effective vaccine …
Allogeneic cytotoxic T-cell therapy for EBV-positive posttransplantation lymphoproliferative disease: results of a phase 2 multicenter clinical trial
T Haque, GM Wilkie, MM Jones… - Blood, The Journal …, 2007 - ashpublications.org
We present the results of a multicenter clinical trial using Epstein-Barr virus (EBV)–specific
cytotoxic T lymphocytes (CTLs) generated from EBV-seropositive blood donors to treat …
cytotoxic T lymphocytes (CTLs) generated from EBV-seropositive blood donors to treat …
Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals
Immunocompromised individuals are at high risk for life-threatening diseases, especially
those caused by cytomegalovirus (CMV), Epstein-Barr virus (EBV) and adenovirus …
those caused by cytomegalovirus (CMV), Epstein-Barr virus (EBV) and adenovirus …
Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells
L Zhao, R He, H Long, B Guo, Q Jia, D Qin, SQ Liu… - Nature medicine, 2018 - nature.com
Impaired immunity in patients with late-stage cancer is not limited to antitumor responses, as
demonstrated by poor vaccination protection and high susceptibility to infection,–. This has …
demonstrated by poor vaccination protection and high susceptibility to infection,–. This has …
[HTML][HTML] Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis
BACKGROUND. Increasing evidence indicates a role for EBV in the pathogenesis of
multiple sclerosis (MS). EBV-infected autoreactive B cells might accumulate in the CNS …
multiple sclerosis (MS). EBV-infected autoreactive B cells might accumulate in the CNS …
Treatment of nasopharyngeal carcinoma with Epstein-Barr virus–specific T lymphocytes
KCM Straathof, CM Bollard, U Popat, MH Huls, T Lopez… - Blood, 2005 - ashpublications.org
Conventional treatment for nasopharyngeal carcinoma (NPC) frequently fails and is
accompanied by severe long-term side effects. Since virtually all undifferentiated NPCs are …
accompanied by severe long-term side effects. Since virtually all undifferentiated NPCs are …
EBV MicroRNAs in Primary Lymphomas and Targeting of CXCL-11 by ebv-mir-BHRF1-3
T Xia, A O'Hara, I Araujo, J Barreto, E Carvalho… - Cancer research, 2008 - AACR
EBV-encoded microRNAs (miRNAs) have been identified and their functions are being
studied. The expression pattern of these miRNAs in clinical samples of EBV-associated non …
studied. The expression pattern of these miRNAs in clinical samples of EBV-associated non …