The “his and hers” of the renin-angiotensin system

LM Hilliard, AK Sampson, RD Brown… - Current hypertension …, 2013 - Springer
Sex differences exist in the regulation of arterial pressure and renal function by the renin-
angiotensin system (RAS). This may in part stem from a differential balance in the pressor …

Genetic polymorphism in angiotensinogen and its association with cardiometabolic diseases

M Shahid, K Rehman, MSH Akash, S Suhail, S Kamal… - Metabolites, 2022 - mdpi.com
Angiotensinogen (AGT) is one of the most significant enzymes of the renin-angiotensin-
aldosterone system (RAAS) which is involved in the regulation and maintenance of blood …

SARS CoV2 infection _The longevity study perspectives

D Lio, L Scola, RM Giarratana, G Candore… - Ageing research …, 2021 - Elsevier
Like other infectious diseases, COVID-19 shows a clinical outcome enormously variable,
ranging from asymptomatic to lethal. In Italy, like in other countries, old male individuals, with …

Gender specific association of RAS gene polymorphism with essential hypertension: a case‐control study

K Dhanachandra Singh, A Jajodia… - BioMed research …, 2014 - Wiley Online Library
Renin‐angiotensin system (RAS) polymorphisms have been studied as candidate risk
factors for hypertension with inconsistent results, possibly due to heterogeneity among …

Gene-based association study reveals a distinct female genetic signal in primary hypertension

R Zucker, M Kovalerchik, M Linial - Human Genetics, 2023 - Springer
Hypertension is a polygenic disease that affects over 1.2 billion adults aged 30–79
worldwide. It is a major risk factor for renal, cerebrovascular, and cardiovascular diseases …

[HTML][HTML] Angiotensinogen (AGT) M235T, AGT T174M and angiotensin-1-converting enzyme (ACE) I/D gene polymorphisms in essential hypertension: effects on …

V Kolovou, E Lagou, C Mihas, G Vasiliki… - The open …, 2015 - ncbi.nlm.nih.gov
Background: Hypertension, one of the most important risk factors for premature
cardiovascular disease, is a major worldwide public health problem. Angiotensin-1 …

Sex differences in abdominal aortic aneurysms

AC Boese, L Chang, KJ Yin, YE Chen… - American Journal …, 2018 - journals.physiology.org
Abdominal aortic aneurysm (AAA) is a vascular disorder with a high case fatality rate in the
instance of rupture. AAA is a multifactorial disease, and the etiology is still not fully …

Gene polymorphisms of angiotensin-converting enzyme and angiotensinogen and risk of idiopathic ischemic stroke

I Isordia-Salas, D Santiago-Germán… - Gene, 2019 - Elsevier
Objective The renin-angiotensin system (RAS) is a hormonal signaling mechanism
implicated in the atherosclerosis and regulation of blood pressure. Angiotensin-converting …

Enlighten the association of Angiotensinogen gene (AGT) polymorphisms and hypertension in Jammu region of north Indian population: A case-control study

M Sharma, JK Raina, M Bhagat, A Sudershan… - Human Gene, 2024 - Elsevier
Background Hypertension is a common cause associated with various life-threatening
disorders such as stroke, heart attack, etc. AGT, with its two common polymorphisms, ie …

Polymorphisms in the Renin-Angiotensin System and eNOS Glu298Asp Genes Are Associated with Increased Risk for Essential Hypertension in a Mexican …

I Isordia-Salas, D Santiago-Germán… - Journal of the Renin …, 2023 - journals.sagepub.com
Background. Essential hypertension is the result of modifiable and genetic factors, and it is
associated with increased risk for atherothrombosis. Some polymorphisms are associated …