Host-targeting therapies for hepatitis C virus infection: current developments and future applications
E Crouchet, F Wrensch, C Schuster… - Therapeutic …, 2018 - journals.sagepub.com
Chronic hepatitis C virus (HCV) infection is a leading cause of chronic liver diseases and
hepatocellular carcinoma (HCC) worldwide. In the past few years, anti-HCV therapies have …
hepatocellular carcinoma (HCC) worldwide. In the past few years, anti-HCV therapies have …
Hepatitis C virus–apolipoprotein interactions: Molecular mechanisms and clinical impact
E Crouchet, TF Baumert, C Schuster - Expert review of proteomics, 2017 - Taylor & Francis
Introduction: Chronic hepatitis C virus (HCV) infection is a leading cause of cirrhosis,
hepatocellular carcinoma and liver failure. Moreover, chronic HCV infection is associated …
hepatocellular carcinoma and liver failure. Moreover, chronic HCV infection is associated …
Genome editing of oncogenes with ZFNs and TALENs: caveats in nuclease design
S Shankar, A Sreekumar, D Prasad, AV Das… - Cancer cell …, 2018 - Springer
Background Gene knockout technologies involving programmable nucleases have been
used to create knockouts in several applications. Gene editing using Zinc-finger nucleases …
used to create knockouts in several applications. Gene editing using Zinc-finger nucleases …
Exploring lipid and apolipoprotein levels in chronic hepatitis C patients according to their response to antiviral treatment
G de Souza Lacerda, T Medeiros, NF do Rosário… - Clinical …, 2018 - Elsevier
Background Hepatitis C virus is known to be highly dependent of lipid metabolism to infect
new cells and replicate. Aims To investigate lipid and apolipoprotein profile in chronic HCV …
new cells and replicate. Aims To investigate lipid and apolipoprotein profile in chronic HCV …
Hepatitis C virus and proprotein convertase subtilisin/kexin type 9: a detrimental interaction to increase viral infectivity and disrupt lipid metabolism
M Pirro, V Bianconi, D Francisci… - Journal of cellular …, 2017 - Wiley Online Library
From viral binding to the hepatocyte surface to extracellular virion release, the replication
cycle of the hepatitis C virus (HCV) intersects at various levels with lipid metabolism; this …
cycle of the hepatitis C virus (HCV) intersects at various levels with lipid metabolism; this …
Mapping intracellular immune responses against lentiviral vectors in natural killer cells using genome scale CRISPR knockout
A Saraç - 2017 - acikbilim.yok.gov.tr
The use of genetically modified cells for therapeutic purposes is an increasing trend that
shows great promise. The major hurdle in genetic modification of human cells is the delivery …
shows great promise. The major hurdle in genetic modification of human cells is the delivery …