Since its first description more than 20 years ago osteopontin has emerged as an active
player in many physiological and pathological processes, including biomineralization, tissue …

The limited durability of resin-dentin bonds severely compromises the lifetime of tooth-
colored restorations. Bond degradation occurs via hydrolysis of suboptimally polymerized …

Tumor-associated macrophages (TAMs) polarization represents a key regulatory process of
tumor progression. However, the underlying mechanisms are unclear. This study aimed to …

The biological roles of the matrix metalloproteinases (MMPs) have been traditionally
associated with the degradation and turnover of most of the components of the extracellular …

Matrix metalloproteinases (MMPs) form a family of enzymes that mediate multiple functions
both in the tissue destruction and immune responses related to periodontal inflammation …

Matrix metalloproteinases (MMPs) are a group of enzymes that in concert are responsible for
the degradation of most extracellular matrix proteins during organogenesis, growth and …

Cell migration and degradation of the extracellular matrix (ECM) are crucial steps in tumor
progression. Several matrix-degrading proteases, including matrix metalloproteases, are …

Although recent data suggests that osteoblasts play a key role within the hematopoietic stem
cell (HSC) niche, the mechanisms underpinning this remain to be fully defined. The studies …

The objective of this review is to summarize our understanding of the role of host matrix
metalloproteinases (MMPs) in the caries process and to discuss new therapeutic avenues …

The activity of matrix metalloproteinases (MMPs) is regulated at several levels, including
enzyme activation, inhibition, complex formation and compartmentalization. Regulation at …