Meningeal lymphatics in central nervous system diseases
AFM Salvador, N Abduljawad… - Annual Review of …, 2024 - annualreviews.org
Since its recent discovery, the meningeal lymphatic system has reshaped our understanding
of central nervous system (CNS) fluid exchange, waste clearance, immune cell trafficking …
of central nervous system (CNS) fluid exchange, waste clearance, immune cell trafficking …
Unraveling the lymphatic system in the spinal cord meninges: a critical element in protecting the central nervous system
S Gonuguntla, J Herz - Cellular and Molecular Life Sciences, 2023 - Springer
The lymphatic vasculature plays a crucial role in fluid clearance and immune responses in
peripheral organs by connecting them to distal lymph nodes. Recently, attention has been …
peripheral organs by connecting them to distal lymph nodes. Recently, attention has been …
Bioactive Peptide Hydrogel Scaffold with High Fluidity, Thermosensitivity, and Neurotropism in 3D Spatial Structure for Promoted Repair of Spinal Cord Injury
Z Sun, X Luan, Z Sun, D Li, H Hu, Q Xue, B Liu, Q Yu… - Small, 2024 - Wiley Online Library
Spinal cord injury (SCI) has been considered a clinically challenging disease that is
characterized by local disturbance of the microenvironment, which inhibits post‐injury neural …
characterized by local disturbance of the microenvironment, which inhibits post‐injury neural …
Differential impact of lymphatic outflow pathways on cerebrospinal fluid homeostasis
Z Papadopoulos, LCD Smyth, I Smirnov… - Journal of Experimental …, 2025 - rupress.org
Dysfunctional lymphatic drainage from the central nervous system (CNS) has been linked to
neuroinflammatory and neurodegenerative disorders, but our understanding of the …
neuroinflammatory and neurodegenerative disorders, but our understanding of the …
Microenvironment Self‐Adaptive Nanomedicine Promotes Spinal Cord Repair by Suppressing Inflammation Cascade and Neural Apoptosis
D Qian, J Xu, X Zhang, F Hu, S Cao, Y Dong… - Advanced …, 2024 - Wiley Online Library
Despite various biomaterial‐based strategies are tried in spinal cord injury (SCI), developing
safe and effective microinvasive pharmacotherapy strategies is still an unmet clinical need …
safe and effective microinvasive pharmacotherapy strategies is still an unmet clinical need …
The “Inner–Outer” Molecules-Loaded Fiber-Hydrogel Scaffolds Coordinate Specific Immunity and Neural Differentiation for Repairing SCI
W Hu, J Luo, C Chen, X Wang, J Niu, H Shen… - ACS Materials …, 2024 - ACS Publications
The treatment of spinal cord injury (SCI) remains unsatisfactory because of the inflammatory
microenvironment and the limited potential for nerve regeneration. However, most …
microenvironment and the limited potential for nerve regeneration. However, most …
Spatial multi-omics analysis of the microenvironment in traumatic spinal cord injury: a narrative review
R Peng, L Zhang, Y Xie, S Guo, X Cao… - Frontiers in …, 2024 - frontiersin.org
Traumatic spinal cord injury (tSCI) is a severe injury to the central nervous system that is
categorized into primary and secondary injuries. Among them, the local microenvironmental …
categorized into primary and secondary injuries. Among them, the local microenvironmental …
[HTML][HTML] Spinal lymphatic dysfunction aggravates the recovery process after spinal cord injury
RG Zhang, BW Zheng, J Zhang, M Hao, YH Diao… - Neuroscience, 2024 - Elsevier
We aimed to evaluate the role of the spinal lymphatic system in spinal cord injury and
whether it has an impact on recovery after spinal cord injury. Flow cytometry was used to …
whether it has an impact on recovery after spinal cord injury. Flow cytometry was used to …
Single‐Nucleus RNA Sequencing Reveals That Gabra6+ Neurons in Prefrontal Cortex Promote the Progression of PTSD After Shockwave‐Induced TBI
X Fei, Z Zhang, Y Dou, W Lv, H Chen… - Advanced …, 2024 - Wiley Online Library
Shockwave‐induced traumatic brain injury (TBI) results in the onset of post‐traumatic stress
disorder (PTSD), triggered either by the TBI itself or other stressors. However, the interplay …
disorder (PTSD), triggered either by the TBI itself or other stressors. However, the interplay …
Endothelial Foxo1 Phosphorylation Inhibition via Aptamer‐Liposome Alleviates OPN‐Induced Pathological Vascular Remodeling Following Spinal Cord Injury
J Xu, C Shi, Y Ding, T Qin, C Li, F Yuan, Y Liu… - Advanced …, 2024 - Wiley Online Library
Reconstruction of the neurovascular unit is essential for the repair of spinal cord injury (SCI).
Nonetheless, detailed documentation of specific vascular changes following SCI and …
Nonetheless, detailed documentation of specific vascular changes following SCI and …