Evaluation of oseltamivir used to prevent hospitalization in outpatients with influenza: a systematic review and meta-analysis
R Hanula, É Bortolussi-Courval, A Mendel… - JAMA Internal …, 2023 - jamanetwork.com
Importance Despite widespread use, summary evidence from prior meta-analyses has
contradictory conclusions regarding whether oseltamivir decreases the risk of hospitalization …
contradictory conclusions regarding whether oseltamivir decreases the risk of hospitalization …
Incidence, risk factors and mortality of invasive pulmonary aspergillosis in patients with influenza: A systematic review and meta‐analysis
C Shi, Q Shan, J Xia, L Wang, L Wang, L Qiu, Y Xie… - Mycoses, 2022 - Wiley Online Library
Background An increasing number of cases of invasive pulmonary aspergillosis (IPA)
complicating influenza have been described. We performed a meta‐analysis to estimate the …
complicating influenza have been described. We performed a meta‐analysis to estimate the …
The REMAP-CAP (randomized embedded multifactorial adaptive platform for community-acquired pneumonia) study. Rationale and design
There is broad interest in improved methods to generate robust evidence regarding best
practice, especially in settings where patient conditions are heterogenous and require …
practice, especially in settings where patient conditions are heterogenous and require …
Acute cardiovascular events associated with influenza in hospitalized adults: a cross-sectional study
EJ Chow, MA Rolfes, A O'Halloran… - Annals of internal …, 2020 - acpjournals.org
Background: Influenza may contribute to the burden of acute cardiovascular events during
annual influenza epidemics. Objective: To examine acute cardiovascular events and …
annual influenza epidemics. Objective: To examine acute cardiovascular events and …
Nebulised ALX-0171 for respiratory syncytial virus lower respiratory tract infection in hospitalised children: a double-blind, randomised, placebo-controlled, phase 2b …
S Cunningham, PA Piedra… - The Lancet …, 2021 - thelancet.com
Background Respiratory syncytial virus (RSV) is the most common cause of severe lower
respiratory tract infection, with a high global health burden. There are no effective treatments …
respiratory tract infection, with a high global health burden. There are no effective treatments …
Combining baloxavir marboxil with standard-of-care neuraminidase inhibitor in patients hospitalised with severe influenza (FLAGSTONE): a randomised, parallel …
Summary Background Neuraminidase inhibitors (NAIs) are considered the standard of care
for hospitalised patients with influenza. We aimed to test whether combining the cap …
for hospitalised patients with influenza. We aimed to test whether combining the cap …
Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model
L Seldeslachts, L Vanderbeke, A Fremau… - Virulence, 2021 - Taylor & Francis
Invasive pulmonary aspergillosis (IPA) is a life-threatening fungal infection occurring mainly
in immunocompromised patients. We recently identified IPA as an emerging co-infection …
in immunocompromised patients. We recently identified IPA as an emerging co-infection …
COVID-19 and therapeutic drugs repurposing in hand: the need for collaborative efforts
The novel pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible to cause coronavirus disease-2019 (COVID-19). It is a global pandemic disease …
responsible to cause coronavirus disease-2019 (COVID-19). It is a global pandemic disease …
Efficacy and mechanism of actions of natural antimicrobial drugs
L Ye, J Zhang, W Xiao, S Liu - Pharmacology & Therapeutics, 2020 - Elsevier
Microbial infections have significantly increased over the last decades, and the mortality
rates remain unacceptably high. The emergence of new resistance patterns and the spread …
rates remain unacceptably high. The emergence of new resistance patterns and the spread …
Neuraminidase is a host‐directed approach to regulate neutrophil responses in sepsis and COVID‐19
R de Oliveira Formiga, FC Amaral… - British Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Neutrophil overstimulation plays a crucial role in tissue
damage during severe infections. Because pathogen‐derived neuraminidase (NEU) …
damage during severe infections. Because pathogen‐derived neuraminidase (NEU) …