Nanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted
cancer therapy due to their ability to overcome many of the key challenges currently being …

One appealing concept in the field of hybrid materials is related to the design of gated
materials. These materials are prepared in such a way that the release of chemical or …

Imprecise targeting of chemotherapeutic drugs often leads to severe toxicity during breast
cancer therapy. To address this issue, we have devised a strategy to load dacarbazine (DC) …

The combination of an immuno-metabolic adjuvant and immune checkpoint inhibitors holds
great promise for effective suppression of tumor growth and invasion. In this study, a pH …

Metformin, a well-acknowledged biguanide, safety profile and multiaction drug with low cost
for management of type 2 diabetes, makes a first-class candidate for repurposing. The off …

Despite cancer nanomedicine celebrates already thirty years since its introduction, together
with the achievements and progress in cancer treatment area, it still undergoes serious …

The most prevalent clinical option for treating cancer is combination chemotherapy. In
combination therapy, assessment and optimization for obtaining a synergistic ratio could be …

In recent years, Onco-immunotherapies (OIMTs) have been shown to be a potential therapy
option for cancer. Several immunotherapies have received regulatory approval, while many …

Topoisomerase enzymes have shown unique roles in replication and transcription. These
enzymes which were initially found in Escherichia coli have attracted considerable attention …

Interest has grown in studying the possible use of well-known anti-diabetic drugs as anti-
cancer agents individually or in combination with, frequently used, chemotherapeutic agents …