Up to 10% of the mouse genome is comprised of endogenous retrovirus (ERV) sequences,
and most represent the remains of ancient germ line infections. Our knowledge of the three …

Endogenous retroviruses (ERVs) differ from typical retroviruses in being inherited through
the host germline and therefore are a unique combination of pathogen and selfish genetic …

Mammalian genomes contain a high load of mobile elements among which long terminal
repeat (LTR)-retrotransposons may represent up to 10% of the genomic DNA. The murine …

Endogenous retroviruses (ERVs) have rewired host gene networks. To explore the origins of
co-option, we employed an active murine ERV, IAPEz, and an embryonic stem cell (ESC) to …

The transcript of retrovirus-like transposons functions as an mRNA for synthesis of capsid
and replication proteins and as the genomic RNA of virus-like particles (VLPs), wherein the …

We had previously identified active autonomous copies of the MusD long terminal repeat-
retrotransposon family, which have retained transpositional activity. These elements are …

Several families of endogenous retroviruses (ERVs) have been identified in the mouse
genome, in several instances by in silico searches, but for many of them it remains to be …

ABSTRACT mRNA-processing bodies (P bodies) are cytoplasmic foci that contain
translationally repressed mRNA. Since they are important for the retrotransposition of Ty …

Transposable elements (TEs) are mobile genetic elements present in every living species.
To limit their harmful effects, species have developed over evolutionary time-scales several …

Hepatitis C virus (HCV) infection is a major cause of chronic hepatitis, liver cirrhosis, and
hepatocellular carcinoma (HCC). Approximately 170 million people are infected worldwide …