Antifungal therapy: new advances in the understanding and treatment of mycosis
L Scorzoni, ACA de Paula e Silva, CM Marcos… - Frontiers in …, 2017 - frontiersin.org
The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …
Antifungal resistance in dermatophytes: Recent trends and therapeutic implications
Dermatophytoses or tinea refers to superficial fungal infection of keratinized tissues.
Although generally considered easy to treat, recalcitrant infections, presenting as extensive …
Although generally considered easy to treat, recalcitrant infections, presenting as extensive …
Major challenges and perspectives in the diagnostics and treatment of dermatophyte infections
S Gnat, D Łagowski… - Journal of applied …, 2020 - academic.oup.com
Dermatophytes are the aetiological factors of a majority of superficial fungal infections. What
distinguishes them from other pathogenic filamentous fungi is their unique ability to degrade …
distinguishes them from other pathogenic filamentous fungi is their unique ability to degrade …
Dermatophyte resistance to antifungal drugs: mechanisms and prospectus
Dermatophytes comprise pathogenic fungi that have a high affinity for the keratinized
structures present in nails, skin, and hair, causing superficial infections known as …
structures present in nails, skin, and hair, causing superficial infections known as …
State-of-the-art dermatophyte infections: epidemiology aspects, pathophysiology, and resistance mechanisms
The burden of fungal infections is not widely appreciated. Although these infections are
responsible for over one million deaths annually, it is estimated that one billion people are …
responsible for over one million deaths annually, it is estimated that one billion people are …
Antifungal resistance mechanisms in dermatophytes
Although fungi do not cause outbreaks or pandemics, the incidence of severe systemic
fungal infections has increased significantly, mainly because of the explosive growth in the …
fungal infections has increased significantly, mainly because of the explosive growth in the …
[HTML][HTML] Dermatophytes: host-pathogen interaction and antifungal resistance
As micoses cutâneas estão entre as infecções mais comuns em humanos e se tornaram um
importante problema de saúde pública, principalmente por causarem infecções invasivas …
importante problema de saúde pública, principalmente por causarem infecções invasivas …
Antimicrobials and resistance part II: Antifungals, antivirals, and antiparasitics
FF Muhaj, SJ George, CD Nguyen, SK Tyring - Journal of the American …, 2022 - Elsevier
The available antifungal armamentarium consists of only a few drug classes, many limited in
their use by significant toxicities and dangerous drug interactions. Rising opportunistic …
their use by significant toxicities and dangerous drug interactions. Rising opportunistic …
Dermatophyte virulence factors: identifying and analyzing genes that may contribute to chronic or acute skin infections
RR Achterman, TC White - International journal of microbiology, 2012 - Wiley Online Library
Dermatophytes are prevalent causes of cutaneous mycoses and, unlike many other fungal
pathogens, are able to cause disease in immunocompetent individuals. They infect …
pathogens, are able to cause disease in immunocompetent individuals. They infect …
Generating and testing molecular hypotheses in the dermatophytes
Dermatophytes are the most common cause of fungal infections worldwide, impacting
millions of individuals annually. In the United States alone, this translates into an economic …
millions of individuals annually. In the United States alone, this translates into an economic …