Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of bone marrow
cells originating from immature myeloid cells. They exert potent immunosuppressive activity …

Chronic lymphocytic leukemia (CLL) cells extensively interact with and depend on their
surrounding tumor microenvironment (TME). The TME encompasses a heterogeneous array …

The immunosuppressive tumor microenvironment (TME) supports the development of
tumors and limits tumor immunotherapy, including hematological malignancies …

Simple Summary Tumor cell-derived extracellular vesicles (TEVs) are an important means of
tumor communication with, and manipulation of, the patient's physiology. TEVs influence the …

The engagement of the B cell receptor (BcR) on the surface of leukemic cells represents a
key event in chronic lymphocytic leukemia (CLL) since it can lead to the maintenance and …

Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and
monocytes that negatively regulate the immune response to cancer and chronic infections …

Myeloid-derived suppressor cells (MDSCs) are a group of bone marrow derived
heterogeneous cells, which is known for their immunosuppressive functions especially in …

Simple Summary In chronic lymphocytic leukemia (CLL), immune alterations—affecting both
the innate and adaptive immunity—are very common. As a clinical consequence, patients …

Myeloid‐derived suppressor cells (MDSCs) are an immature group of myeloid‐derived cells
generated from myeloid cell precursors in the bone marrow. MDSCs appear almost …

Evidence suggests that neutrophils exert specialized effector functions during infection and
inflammation, and that these cells can affect the duration, severity, and outcome of the …