Biological importance of structurally diversified chromenes

M Costa, TA Dias, A Brito, F Proença - European journal of medicinal …, 2016 - Elsevier
Compounds incorporating the chromene scaffold are largely present in natural products and
display a wide variety of biological activities. Their low toxicity combined to the broad …

[HTML][HTML] Therapeutic options for management of endometrial hyperplasia

V Chandra, JJ Kim, DM Benbrook… - Journal of …, 2016 - synapse.koreamed.org
Endometrial hyperplasia (EH) comprises a spectrum of changes in the endometrium ranging
from a slightly disordered pattern that exaggerates the alterations seen in the late …

[HTML][HTML] Niclosamide causes lysosome-dependent cell death in endometrial cancer cells and tumors.

R Rai, DK Dey, DM Benbrook, V Chandra - Biomedicine & …, 2023 - Elsevier
Endometrial cancer is the most common female cancer showing continuous rise in its
incidence and mortality rate. Despite the extensive research efforts in cancer therapeutics …

[HTML][HTML] Inhibitory effect of 2-(piperidinoethoxyphenyl)-3-(4-hydroxyphenyl)-2H-benzo (b) pyran (K-1) on human primary endometrial hyperplasial cells mediated via …

V Chandra, I Fatima, M Manohar, P Popli… - Cell death & …, 2014 - nature.com
Endometrial hyperplasia is a precursor to the most common gynecologic cancer diagnosed
in women. Apart from estrogenic induction, aberrant activation of the Wnt/β-catenin signal is …

Positive skeletal effects of cladrin, a naturally occurring dimethoxydaidzein, in osteopenic rats that were maintained after treatment discontinuation

K Khan, K Sharan, G Swarnkar, B Chakravarti… - Osteoporosis …, 2013 - Springer
Effects of cladrin treatment and withdrawal in osteopenic rats were studied. Cladrin
improved trabecular microarchitecture, increased lumbar vertebral compressive strength …

Jab1-siRNA induces cell growth inhibition and cell cycle arrest in gall bladder cancer cells via targeting Jab1 signalosome

P Pandey, MH Siddiqui, A Behari… - Anti-Cancer Agents …, 2019 - ingentaconnect.com
Background: The aberrant alteration in Jab1 signalosome (COP9 Signalosome Complex
Subunit 5) has been proven to be associated with the progression of several carcinomas …

[HTML][HTML] Молекулярно-генетические характеристики пациенток с гиперплазией и полипами эндометрия

НА Демакова - Научные результаты биомедицинских …, 2018 - cyberleninka.ru
Актуальность. Гиперпластические процессы эндометрия (ГПЭ) являются одними из
наиболее частых гинекологических заболеваний, приводят к потере репродуктивной …

[HTML][HTML] The regulation of Hh/Gli1 signaling cascade involves Gsk3β-mediated mechanism in estrogen-derived endometrial hyperplasia

JB Kaushal, P Sankhwar, S Kumari, P Popli, V Shukla… - Scientific reports, 2017 - nature.com
The present study was undertaken to explore the functional involvement of Hh signaling and
its regulatory mechanism in endometrial hyperplasia. Differential expression of Hh signaling …

[HTML][HTML] Молекулярные основы этиопатогенеза и клиники эндометриоза

ИВ Пономаренко, ОА Конева… - Актуальные проблемы …, 2016 - cyberleninka.ru
Эндометриоз хроническое гинекологическое заболевание, главными клиническими
проявлениями которого является персистирующая боль и бесплодие представляет …

The anti-proliferative effect of 2-[piperidinoethoxyphenyl]-3-[4-hydroxyphenyl]-2H-benzo (b) pyran is potentiated via induction of estrogen receptor beta and p21 in …

I Fatima, R Saxena, G Kharkwal, MK Hussain… - The Journal of Steroid …, 2013 - Elsevier
In an effort to develop novel therapeutic agents for endometrial cancer, benzopyran
derivatives synthesized at our institute display significant inhibitory activity on cellular growth …