Significance: Thioredoxin (Trx) is a powerful antioxidant that reduces protein disulfides to
maintain redox stability in cells and is involved in regulating multiple redox-dependent …

Since the spread of the deadly virus SARS-CoV-2 in late 2019, researchers have restlessly
sought to unravel how the virus enters the host cells. Some proteins on each side of the …

In this study, a novel label-free electrochemical biosensor based on the zeolitic imidazole
framework (ZIF-8) was developed for monitoring protein–protein interactions (PPIs). ZIF-8 …

Despite significantly improved clinical outcomes in EGFR-mutant lung adenocarcinoma, all
patients develop acquired resistance and malignancy on the treatment of EGFR tyrosine …

Background Protein cysteine oxidation is substantially involved in various biological and
pathogenic processes, but its implications in pancreatic cancer development remains poorly …

Scavenger receptor A (SRA) is preferentially expressed in macrophages and implicated as a
multifunctional pattern recognition receptor for innate immunity. Hepatic macrophages play a …

Proteolysis represents a posttranslational modification, which irreversibly changes the
structure of targeted proteins. Consequently, peptides generated by proteolytic processing …