Nasopharyngeal carcinoma is an umbrella term for a group of malignant epithelial tumors
with different etiopathogenesis and a broad range of histopathological appearances. Some …

3854 growth factors. The mitogen-activated protein kinases (MAPKs) play a major role in
mitogenic signaling, and the canonical Ras-Raf-MEK [MAPK and extracellular signal …

Nasopharyngeal carcinoma (NPC) is a head and neck cancer rare throughout most of the
world but common in certain geographic areas, such as southern Asia. While environmental …

The proliferating cell nuclear antigen (PCNA) is an essential protein for DNA replication and
damage repair. How its function is controlled remains an important question. Here, we show …

MicroRNAs (miRNAs) are a family of small non-coding RNA molecules of about 20–23
nucleotides in length, which negatively regulate protein-coding genes at post-transcriptional …

Nasopharyngeal carcinoma (NPC) differs from other head and neck cancers in its aetiology,
epidemiology and potential therapeutic options. Despite cure for the majority of the patients …

Chronic inflammation induced by biological, chemical, and physical factors has been found
to be associated with the increased risk of cancer in various organs. We revealed that …

Background & Aims: Wnt/β-catenin activation is observed in normal liver development,
regeneration, and liver cancer. Our aim was to elucidate the regulation and mechanism of …

Integral membrane proteins contain a hydrophobic transmembrane domain and mainly
locate in the plasma membrane lipid bilayer. The receptor tyrosine kinases (RTK) of the …

Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) has been known to
have oncogenic properties during latent infection in nasopharyngeal carcinoma (NPC). Our …