[HTML][HTML] Advances in extraction methods, chemical constituents, pharmacological activities, molecular targets and toxicology of volatile oil from Acorus calamus var …

D Bai, X Li, S Wang, T Zhang, Y Wei, Q Wang… - Frontiers in …, 2022 - frontiersin.org
Acorus calamus var. angustatus Besser (ATT) is a traditional herb with a long medicinal
history. The volatile oil of ATT (VOA) does possess many pharmacological activities. It can …

[HTML][HTML] Dehydrocostus lactone suppresses dextran sulfate sodium-induced colitis by targeting the IKKα/β-NF-κB and Keap1-Nrf2 signalling pathways

Y Yuan, Q Hu, L Liu, F Xie, L Yang, Y Li… - Frontiers in …, 2022 - frontiersin.org
Dehydrocostus lactone (DCL) is a major sesquiterpene lactone isolated from Aucklandia
lappa Decne, a traditional Chinese herbal medicine that used to treat gastrointestinal …

[HTML][HTML] Isoalantolactone protects against ethanol-induced gastric ulcer via alleviating inflammation through regulation of PI3K-Akt signaling pathway and Th17 cell …

C Zhou, J Chen, K Liu, K Maharajan, Y Zhang… - Biomedicine & …, 2023 - Elsevier
Gastric ulcer (GU) is one of the most prevalent digestive system diseases in humans, and it
has been linked to inflammation. Previous studies have demonstrated the anti-inflammatory …

Recent advances of sesquiterpenoid dimers from Compositae: distribution, chemistry and biological activities

FC Meng, Z Wang, SJ Peng, GG Zhou, A Khalid… - Phytochemistry …, 2024 - Springer
Composite family contains a wide variety of plants and many of them possess high
medicinal value. Various constituents have been isolated from members of Composite …

Sesquiterpene lactones-rich fraction from Aucklandia lappa Decne. alleviates dextran sulfate sodium induced ulcerative colitis through co-regulating MAPK and Nrf2 …

Y Chen, Z Miao, X Sheng, X Li, J Ma, X Xu, H Li… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Aucklandia lappa Decne.(ALDE) is the general
name for Asteraceae plants Yunmuxiang, which has traditionally been proven to have the …

Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages

J He, L Liu, X Liu, H Chen, K Liu, N Huang… - International …, 2022 - Elsevier
Ulcerative colitis (UC) is an unspecific colorectal inflammation associated with macrophages
overactivation. Therefore, macrophage-targeted treatment has been considered a promising …

Targeted isolation of sesquiterpene lactone dimers from Aucklandia lappa guided by LC-HRMS/MS-based molecular networking

JS Han, JG Kim, TPL Le, YB Cho, D Lee, JT Hong… - Phytochemistry, 2023 - Elsevier
Abstract An LC-HRMS/MS-based molecular networking strategy was applied to investigate
the potential sesquiterpene dimers of Aucklandia lappa, leading to the isolation of three …

Dehydrocostus lactone alleviates irinotecan-induced intestinal mucositis by blocking TLR4/MD2 complex formation

M Sun, H Zhan, X Long, AM Alsayed, Z Wang, F Meng… - Phytomedicine, 2024 - Elsevier
Abstract Background Irinotecan (CPT-11) is used as chemotherapeutic drug for treatment of
colorectal cancer. However, without satisfactory treatments, its gastrointestinal toxicities such …

Selection and evaluation of quality markers (Q-markers) of vladimiriae radix extract for cholestatic liver injury based on spectrum-effect relationship, pharmacokinetics …

C Wei, L Wu, Y Wu, C Xu, H Hu, Z Wang - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance As a representative local medicinal herb produced in
China, Vladimiriae Radix (VR) has been proven to exert hepatoprotective and choleretic …

Efficacy and Safety of Acupuncture Combined with Yishen Granule in Elderly Adults with Mild Cognitive Impairment: A Multicenter, Randomized Controlled Trial.

N Li, O Li, Z Sha, Y Wang, Z Li, Y Li… - … Therapies in Health …, 2023 - search.ebscohost.com
Objective• Mild cognitive impairment (MCI) is a clinical disease that is prevalent in the
elderly. Traditional Chinese herbs (TCHs) and acupuncture are valuable therapeutic options …