Primary immunodeficiencies (PIDs), a heterogenous group of inborn errors of immunity, are
predetermined at birth but may evolve with age, leading to a variable clinical and laboratory …

Inborn errors of immunity (IEI), formerly known as primary immunodeficiency disorders
(PIDs), are inherited disorders caused by damaging germline variants in single genes …

Inborn errors of immunity (IEI) are genetic disorders characterized by a wide spectrum of
clinical manifestations, ranging from increased susceptibility to infections to significant …

Autoimmune diseases are usually associated with environmental triggers and genetic
predisposition. However, a few number of autoimmune diseases has a monogenic cause …

Inborn errors of immunity (IEI), caused by hereditary or genetic defects, are a group of more
than 400 disorders, in which the immune system, including lymphocytes, neutrophils …

Inborn errors of immunity (IEIs) are monogenic disorders that predispose patients to immune
dysregulation, autoimmunity, and infection. Autoimmune cytopenias, such as immune …

Introduction: Inborn errors of immunity (IEIs) are inherited disorders that present with
increased susceptibility to infections as well as noninfectious complications. Due to the …

Abstract Juvenile Idiopathic Arthritis (JIA) is sometimes considered a diagnosis of exclusion
as the name signifies that no cause is evident for this form of arthritis. Despite this JIA has …

Background Autoimmune hemolytic anemia (AIHA) is a rare, life-threatening disease in
pediatrics. This article describes the clinical features, diagnostic workup, treatment and …

Abstract Background Patients with partial DiGeorge syndrome (pDGS) can present with
immune dysregulation, the most common being autoimmune cytopenia (AIC). There is a lack …