Abstract High-speed three-dimensional (3D) intravital imaging in animals is useful for
studying transient subcellular interactions and functions in health and disease. Light-field …

Abstract 3D microscopy is a useful tool to visualize the detailed structures and mechanisms
of biomedical specimens. In particular, biophysical phenomena such as neural activity …

With the development of a wide variety of animal models in recent years, there is a rapidly
growing demand for long-term, high-speed intravital fluorescence imaging to observe …

Antidepressants are one of the most commonly prescribed pharmaceutical classes for the
treatment of psychiatric conditions. They act via modulation of brain monoaminergic …

Here we report SUPPORT (statistically unbiased prediction utilizing spatiotemporal
information in imaging data), a self-supervised learning method for removing Poisson …

Motor systems must continuously adapt their output to maintain a desired trajectory. While
the spinal circuits underlying rhythmic locomotion are well described, little is known about …

The extraction of spatiotemporal neuron activity from calcium imaging videos plays a crucial
role in unraveling the coding properties of neurons. While existing neuron extraction …

Interrogation of subcellular biological dynamics occurring in a living cell often requires
noninvasive imaging of the fragile cell with high spatiotemporal resolution across all three …

Optical recordings of neuronal activity at cellular resolution represent an invaluable tool to
investigate brain mechanisms. Zebrafish larvae is one of the few model organisms where …

Deep volumetric microscopy of live objects plays a critical role in biology and medicine. To
this end, development of rapid and non-invasive optical methods for 3-dimensional (3D) …