Pathophysiology of acute respiratory distress syndrome and COVID-19 lung injury

KE Swenson, ER Swenson - Critical care clinics, 2021 - criticalcare.theclinics.com
Acute respiratory distress syndrome (ARDS) is a complex syndrome of acute lung injury
leading to noncardiogenic pulmonary edema from many causes that is heterogenous in its …

Potential protective mechanisms of green tea polyphenol EGCG against COVID-19

Z Zhang, X Zhang, K Bi, Y He, W Yan, CS Yang… - Trends in food science & …, 2021 - Elsevier
Background The world is in the midst of the COVID-19 pandemic. In this comprehensive
review, we discuss the potential protective effects of (−)-epigallocatechin-3-gallate (EGCG) …

[HTML][HTML] Decreased availability of nitric oxide and hydrogen sulfide is a hallmark of COVID-19

P Dominic, J Ahmad, R Bhandari, S Pardue… - Redox biology, 2021 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is involved in
a global outbreak affecting millions of people who manifest a variety of symptoms …

Attenuation of clinical and immunological outcomes during SARS‐CoV‐2 infection by ivermectin

GD de Melo, F Lazarini, F Larrous, L Feige… - EMBO molecular …, 2021 - embopress.org
The devastating pandemic due to SARS‐CoV‐2 and the emergence of antigenic variants
that jeopardize the efficacy of current vaccines create an urgent need for a comprehensive …

Effect of SARS-CoV-2 proteins on vascular permeability

R Rauti, M Shahoha, Y Leichtmann-Bardoogo… - Elife, 2021 - elifesciences.org
Severe acute respiratory syndrome (SARS)-CoV-2 infection leads to severe disease
associated with cytokine storm, vascular dysfunction, coagulation, and progressive lung …

Evidence of pulmonary hypertension after SARS-CoV-2 infection in subjects without previous significant cardiovascular pathology

C Tudoran, M Tudoran, VE Lazureanu… - Journal of Clinical …, 2021 - mdpi.com
Background: Coronavirus (Covid-19) infection represents a serious medical condition, often
associated with cardiovascular complications, pulmonary hypertension (PH), and right …

Brain positron emission tomography (PET) and cognitive abnormalities one year after COVID-19

R Ferrucci, L Cuffaro, A Capozza, C Rosci… - Journal of …, 2023 - Springer
Emerging evidence indicates that the etiologic agent responsible for coronavirus disease
2019 (COVID-19), can cause neurological complications. COVID-19 may induce cognitive …

Functional pathophysiology of SARS-CoV-2-induced acute lung injury and clinical implications

NM Habashi, L Camporota… - Journal of applied …, 2021 - journals.physiology.org
The worldwide pandemic caused by the SARS-CoV-2 virus has resulted in over 84,407,000
cases, with over 1,800,000 deaths when this paper was submitted, with comorbidities such …

COVID‐19, microthromboses, inflammation, and platelet activating factor

C Demopoulos, S Antonopoulou, TC Theoharides - Biofactors, 2020 - Wiley Online Library
Recent articles report elevated markers of coagulation, endothelial injury, and
microthromboses in lungs from deceased COVID‐19 patients. However, there has been no …

SARS-CoV-2 spike protein induces IL-18-mediated cardiopulmonary inflammation via reduced mitophagy

S Liang, C Bao, Z Yang, S Liu, Y Sun, W Cao… - … and Targeted Therapy, 2023 - nature.com
Cardiopulmonary complications are major drivers of mortality caused by the SARS-CoV-2
virus. Interleukin-18, an inflammasome-induced cytokine, has emerged as a novel mediator …