Dopamine reward prediction-error signalling: a two-component response

W Schultz - Nature reviews neuroscience, 2016 - nature.com
Environmental stimuli and objects, including rewards, are often processed sequentially in
the brain. Recent work suggests that the phasic dopamine reward prediction-error response …

Neuronal reward and decision signals: from theories to data

W Schultz - Physiological reviews, 2015 - journals.physiology.org
Rewards are crucial objects that induce learning, approach behavior, choices, and
emotions. Whereas emotions are difficult to investigate in animals, the learning function is …

Prefrontal cortex as a meta-reinforcement learning system

JX Wang, Z Kurth-Nelson, D Kumaran, D Tirumala… - Nature …, 2018 - nature.com
Over the past 20 years, neuroscience research on reward-based learning has converged on
a canonical model, under which the neurotransmitter dopamine 'stamps in'associations …

Persistent spiking activity underlies working memory

C Constantinidis, S Funahashi, D Lee… - Journal of …, 2018 - Soc Neuroscience
Persistent activity generated in the PFC during the delay period of working memory tasks
represents information about stimuli held in memory and determines working memory …

Decoding internally generated transitions of conscious contents in the prefrontal cortex without subjective reports

V Kapoor, A Dwarakanath, S Safavi, J Werner… - Nature …, 2022 - nature.com
A major debate about the neural correlates of conscious perception concerns its cortical
organization, namely, whether it includes the prefrontal cortex (PFC), which mediates …

Context-dependent computation by recurrent dynamics in prefrontal cortex

V Mante, D Sussillo, KV Shenoy, WT Newsome - nature, 2013 - nature.com
Prefrontal cortex is thought to have a fundamental role in flexible, context-dependent
behaviour, but the exact nature of the computations underlying this role remains largely …

Neural mechanisms of movement planning: motor cortex and beyond

K Svoboda, N Li - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Preparatory activity is a neural correlate of motor planning.•Multiple brain areas
cooperate to maintain preparatory activity.•Preparatory activity sets network activity to an …

The speed-accuracy tradeoff: history, physiology, methodology, and behavior

RP Heitz - Frontiers in neuroscience, 2014 - frontiersin.org
There are few behavioral effects as ubiquitous as the speed-accuracy tradeoff (SAT). From
insects to rodents to primates, the tendency for decision speed to covary with decision …

Not so spontaneous: Multi-dimensional representations of behaviors and context in sensory areas

L Avitan, C Stringer - Neuron, 2022 - cell.com
Sensory areas are spontaneously active in the absence of sensory stimuli. This
spontaneous activity has long been studied; however, its functional role remains largely …

Distinct relationships of parietal and prefrontal cortices to evidence accumulation

TD Hanks, CD Kopec, BW Brunton, CA Duan, JC Erlich… - Nature, 2015 - nature.com
Gradual accumulation of evidence is thought to be fundamental for decision-making, and its
neural correlates have been found in several brain regions,,,,,,,. Here we develop a …