Currently, the most effective therapy for acute liver failure and advanced cirrhosis is liver
transplantation. However, this procedure has several limitations, including lack of donors …

Mesenchymal stem cells (MSC) are a group of clonogenic cells present among the bone
marrow stroma and capable of multilineage differentiation into mesoderm-type cells such as …

Background End-stage liver disease is a medical problem with high morbidity and mortality.
We have investigated the feasibility, safety, and efficacy of using autologous mesenchymal …

OBJECTIVE:: To study the effect of mesenchymal stem cells (MSC) on experimental liver
fibrosis in rats. DESIGN AND METHOD:: MSC were derived from bone marrow obtained …

Osteoblasts are key components of the bone multicellular unit and have a seminal role in
bone remodeling, which is an essential function for the maintenance of the structural …

Yes-associated protein (YAP) is a downstream effector of the Hippo signaling pathway,
which controls organ expansion and tissue development. We have recently defined the …

Mesenchymal stem cells (MSCs) possess a set of several fairly unique properties which
make them ideally suited both for cellular therapies/regenerative medicine, and as vehicles …

Stem cells are a unique source of self-renewing cells within the human body. Before the end
of the last millennium, adult stem cells, in contrast to their embryonic counterparts, were …

Mesenchymal stem cells (MSCs) play a crucial role in regulating normal skeletal
homeostasis and, in case of injury, in bone healing and reestablishment of skeletal integrity …

Cbfa1/Runx2 is a bone transcription factor homologous to the Drosophila protein, Runt.
Runx2 is a master gene that encodes for a protein involved in the osteogenic differentiation …