The oxytocin receptor: from intracellular signaling to behavior
B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …
The biology of mammalian parenting and its effect on offspring social development
JK Rilling, LJ Young - Science, 2014 - science.org
Parents know the transformative nature of having and caring for a child. Among many
mammals, giving birth leads from an aversion to infant stimuli to irresistible attraction. Here …
mammals, giving birth leads from an aversion to infant stimuli to irresistible attraction. Here …
Statistical and methodological considerations for the interpretation of intranasal oxytocin studies
Over the last decade, oxytocin (OT) has received focus in numerous studies associating
intranasal administration of this peptide with various aspects of human social behavior …
intranasal administration of this peptide with various aspects of human social behavior …
Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism
Mouse models of neuropsychiatric diseases provide a platform for mechanistic
understanding and development of new therapies. We previously demonstrated that …
understanding and development of new therapies. We previously demonstrated that …
Oxytocin and social relationships: from attachment to bond disruption
Social relationships throughout life are vital for well-being and physical and mental health. A
significant amount of research in animal models as well as in humans suggests that oxytocin …
significant amount of research in animal models as well as in humans suggests that oxytocin …
Can oxytocin treat autism?
LJ Young, CE Barrett - Science, 2015 - science.org
The US Centers for Disease Control and Prevention estimates the prevalence of autism
spectrum disorders (ASDs) to be 1 in 68 children in the United States, yet no drugs to treat …
spectrum disorders (ASDs) to be 1 in 68 children in the United States, yet no drugs to treat …
Neurobiological mechanisms of social attachment and pair bonding
ZV Johnson, LJ Young - Current opinion in behavioral sciences, 2015 - Elsevier
Highlights•Social monogamy has evolved independently in distant species.•Pair bonding
has been investigated most rigorously in prairie voles.•Pair bonding is regulated by …
has been investigated most rigorously in prairie voles.•Pair bonding is regulated by …
Comparative perspectives on oxytocin and vasopressin receptor research in rodents and primates: translational implications
SM Freeman, LJ Young - Journal of neuroendocrinology, 2016 - Wiley Online Library
In the last several decades, sophisticated experimental techniques have been used to
determine the neurobiology of the oxytocin and vasopressin systems in rodents. Using a …
determine the neurobiology of the oxytocin and vasopressin systems in rodents. Using a …
RNAi knockdown of oxytocin receptor in the nucleus accumbens inhibits social attachment and parental care in monogamous female prairie voles
AC Keebaugh, CE Barrett, JL Laprairie… - Social …, 2015 - Taylor & Francis
Oxytocin modulates many aspects of social cognition and behaviors, including maternal
nurturing, social recognition and bonding. Natural variation in oxytocin receptor (OXTR) …
nurturing, social recognition and bonding. Natural variation in oxytocin receptor (OXTR) …
The oxytocin system promotes resilience to the effects of neonatal isolation on adult social attachment in female prairie voles
CE Barrett, SE Arambula, LJ Young - Translational psychiatry, 2015 - nature.com
Genes and social experiences interact to create variation in social behavior and vulnerability
to develop disorders of the social domain. Socially monogamous prairie voles display …
to develop disorders of the social domain. Socially monogamous prairie voles display …