AI on a chip

A Isozaki, J Harmon, Y Zhou, S Li, Y Nakagawa… - Lab on a Chip, 2020 - pubs.rsc.org
Artificial intelligence (AI) has dramatically changed the landscape of science, industry,
defence, and medicine in the last several years. Supported by considerably enhanced …

Bioproducts From Euglena gracilis: Synthesis and Applications

A Gissibl, A Sun, A Care, H Nevalainen… - … in bioengineering and …, 2019 - frontiersin.org
In recent years, the versatile phototrophic protist Euglena gracilis has emerged as an
interesting candidate for application-driven research and commercialisation, as it is an …

High-speed fluorescence image–enabled cell sorting

D Schraivogel, TM Kuhn, B Rauscher… - Science, 2022 - science.org
Fast and selective isolation of single cells with unique spatial and morphological traits
remains a technical challenge. Here, we address this by establishing high-speed image …

Recent advances in single-cell analysis by mass spectrometry

L Yin, Z Zhang, Y Liu, Y Gao, J Gu - Analyst, 2019 - pubs.rsc.org
Cells are the most basic structural units that play vital roles in the functioning of living
organisms. Analysis of the chemical composition and content of a single cell plays a vital …

A practical guide to intelligent image-activated cell sorting

A Isozaki, H Mikami, K Hiramatsu, S Sakuma, Y Kasai… - Nature protocols, 2019 - nature.com
Intelligent image-activated cell sorting (iIACS) is a machine-intelligence technology that
performs real-time intelligent image-based sorting of single cells with high throughput. iIACS …

Ultrafast subcellular biolabeling and bioresponsive real-time monitoring for targeting cancer theranostics

K Huang, Y Wang, Z Qin, H Liu, H Zhang, J Wang… - ACS …, 2023 - ACS Publications
Cell heterogeneity poses a formidable challenge for tumor theranostics, requiring high-
resolution strategies for intercellular bioanalysis between single cells. Nanoelectrode-based …

Quantitative phase imaging flow cytometry for ultra‐large‐scale single‐cell biophysical phenotyping

KCM Lee, M Wang, KSE Cheah, GCF Chan… - Cytometry Part …, 2019 - Wiley Online Library
Cellular biophysical properties are the effective label‐free phenotypes indicative of
differences in cell types, states, and functions. However, current biophysical phenotyping …

Lab on a particle technologies

R Ghosh, A Arnheim, M van Zee, L Shang… - Analytical …, 2024 - ACS Publications
From “Lab on a Chip” to “Lab on a Particle”. The miniaturization and automation of life
science laboratory operations has leveraged fabrication advances in the integrated circuit …

Impedance-based tracking of the loss of intracellular components in microalgae cells

T Tang, X Liu, Y Yuan, T Zhang, R Kiya… - Sensors and Actuators B …, 2022 - Elsevier
Cell staining is a typical procedure for assessing the distribution and density of intracellular
components. In this work, a label-free alternative is developed and verified using impedance …

High-throughput functional profiling of single adherent cells via hydrogel drop-screen

M Wang, MH Nai, RYJ Huang, HL Leo, CT Lim… - Lab on a Chip, 2021 - pubs.rsc.org
Single-adherent-cell phenotyping on an extracellular matrix (ECM) is essential to determine
cellular biological functions, such as morphological adaptations and biomolecule secretions …