Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Insight into Acinetobacter baumannii: pathogenesis, global resistance, mechanisms of resistance, treatment options, and alternative modalities

M Asif, IA Alvi, SU Rehman - Infection and drug resistance, 2018 - Taylor & Francis
Acinetobacter baumannii, once considered a low-category pathogen, has emerged as an
obstinate infectious agent. The scientific community is paying more attention to this …

The current burden of carbapenemases: review of significant properties and dissemination among gram-negative bacteria

D Hammoudi Halat, C Ayoub Moubareck - Antibiotics, 2020 - mdpi.com
Carbapenemases are β-lactamases belonging to different Ambler classes (A, B, D) and can
be encoded by both chromosomal and plasmid-mediated genes. These enzymes represent …

Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii

CO Vrancianu, I Gheorghe, IB Czobor, MC Chifiriuc - Microorganisms, 2020 - mdpi.com
Antibiotic resistance is one of the biggest challenges for the clinical sector and industry,
environment and societal development. One of the most important pathogens responsible …

Overcoming the rising incidence and evolving mechanisms of antibiotic resistance by novel drug delivery approaches–an overview

CKC Lai, RWY Ng, SSY Leung, M Hui, M Ip - Advanced Drug Delivery …, 2022 - Elsevier
Antimicrobial resistance is a normal evolutionary process for microorganisms. Antibiotics
exerted accelerated selective pressure that hasten bacterial resistance through mutation …

Understanding the epidemiology of multi-drug resistant gram-negative bacilli in the Middle East using a one health approach

I Dandachi, A Chaddad, J Hanna, J Matta… - Frontiers in …, 2019 - frontiersin.org
In the last decade, extended-spectrum cephalosporin and carbapenem resistant Gram-
negative bacilli (GNB) have been extensively reported in the literature as being …

Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii with Special Reference to Carbapenemases: A Systematic Review

N Gupta, K Angadi, S Jadhav - Infection and Drug Resistance, 2022 - Taylor & Francis
Carbapenemases are β-lactamase enzymes that hydrolyze a variety of β-lactams including
carbapenem and belong to different Ambler classes (A, B, D). These enzymes can be …

Prevalence of Acinetobacter baumannii in Saudi Arabia: risk factors, antimicrobial resistance patterns and mechanisms of carbapenem resistance

ME Ibrahim - Annals of clinical microbiology and antimicrobials, 2019 - Springer
Acinetobacter baumannii is an important opportunistic pathogen due to its capabilities for
developing mechanisms of resistance to a wide range of antimicrobial agents including …

The Prevalence of Multidrug-Resistant Acinetobacter baumannii and Its Vaccination Status among Healthcare Providers

A Elbehiry, E Marzouk, I Moussa, Y Mushayt… - Vaccines, 2023 - mdpi.com
There is growing concern among healthcare providers worldwide regarding the prevalence
of multidrug-resistant Acinetobacter baumannii (A. baumannii). Some of the worst hospital …

Insight into carbapenem resistance and virulence of Acinetobacter baumannii from a children's medical centre in eastern China

Y Zhu, X Zhang, Y Wang, Y Tao, X Shao, Y Li… - Annals of clinical …, 2022 - Springer
Carbapenem-resistant Acinetobacter baumannii (CRAB) appeared more frequently in
children and caused a great threat to global public health. It is urgent to investigate the …