Antitumoral activity of quinoxaline derivatives: A systematic review

M Montana, F Mathias, T Terme, P Vanelle - European journal of medicinal …, 2019 - Elsevier
Cancer is a leading cause of death and a major health problem worldwide. While many
effective anticancer agents are available, the majority of drugs currently on the market are …

Quinoxaline: An insight into the recent pharmacological advances

S Tariq, K Somakala, M Amir - European Journal of Medicinal Chemistry, 2018 - Elsevier
Quinoxaline, a fused heterocycle of benzene and pyrazine rings has gained considerable
attention in the field of contemporary medicinal chemistry. The moiety is of substantial …

New quinoxaline-based VEGFR-2 inhibitors: Design, synthesis, and antiproliferative evaluation with in silico docking, ADMET, toxicity, and DFT studies

MM Alanazi, H Elkady, NA Alsaif, AJ Obaidullah… - RSC …, 2021 - pubs.rsc.org
A new series of 3-methylquinoxaline-based derivatives having the same essential
pharmacophoric features as VEGFR-2 inhibitors have been synthesized and evaluated for …

[HTML][HTML] Quinoxaline: A comprehension of current pharmacological advancement in medicinal chemistry

SK Suthar, NS Chundawat, GP Singh… - European Journal of …, 2022 - Elsevier
Quinoxaline is a fused heterocycle ring template present in diverse pharmacophore and
widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several …

Quinoxaline derivatives as antiviral agents: a systematic review

M Montana, V Montero, O Khoumeri, P Vanelle - Molecules, 2020 - mdpi.com
Background: In recent decades, several viruses have jumped from animals to humans,
triggering sizable outbreaks. The current unprecedent outbreak SARS-COV-2 is prompting a …

Sulfonic acid-functionalized mesoporous silica (SBA-Pr-SO3H) as solid acid catalyst in organic reactions

GM Ziarani, N Lashgari, A Badiei - Journal of Molecular Catalysis A …, 2015 - Elsevier
Mesoporous silica SBA-15 has been functionalized with sulfonic acid to create highly
powerful heterogeneous solid acid catalysts (SBA-Pr-SO 3 H). The catalyst can be easily …

An insight into medicinal chemistry of anticancer quinoxalines

T Kaushal, G Srivastava, A Sharma, AS Negi - Bioorganic & Medicinal …, 2019 - Elsevier
Quinoxalines are benzopyrazines containing benzene and pyrazine rings fused together. In
the recent past, quinoxalines have attracted Medicinal Chemists considerably for their …

Novel synthetic routes to prepare biologically active quinoxalines and their derivatives: A synthetic review for the last two decades

H Khatoon, E Abdulmalek - Molecules, 2021 - mdpi.com
Quinoxalines, a class of N-heterocyclic compounds, are important biological agents, and a
significant amount of research activity has been directed towards this class. They have …

Present status of quinoxaline motifs: Excellent pathfinders in therapeutic medicine

OO Ajani - European journal of medicinal chemistry, 2014 - Elsevier
Quinoxalines belong to a class of excellent heterocyclic scaffolds owing to their wide
biological properties and diverse therapeutic applications in medicinal research. They are …

Benzodiazines: recent synthetic advances

T Mathew, AÁ Papp, F Paknia, S Fustero… - Chemical Society …, 2017 - pubs.rsc.org
Benzodiazines (diazonaphthalenes with both nitrogens in the same ring)–cinnolines (1, 2-
benzodiazine), quinazolines (1, 3-benzodiazine), phthalazines (2, 3-benzodiazine) and …