Liposomes and lipid bilayers in biosensors

F Mazur, M Bally, B Städler, R Chandrawati - Advances in colloid and …, 2017 - Elsevier
Biosensors for the rapid, specific, and sensitive detection of analytes play a vital role in
healthcare, drug discovery, food safety, and environmental monitoring. Although a number …

Physicochemical characteristics of droplet interface bilayers

Y Huang, GG Fuller, VC Suja - Advances in Colloid and Interface Science, 2022 - Elsevier
Droplet interface bilayer (DIB) is a lipid bilayer formed when two lipid monolayer-coated
aqueous droplets are brought in contact within an oil phase. DIBs, especially post …

Sculpting and fusing biomimetic vesicle networks using optical tweezers

G Bolognesi, MS Friddin, A Salehi-Reyhani… - Nature …, 2018 - nature.com
Constructing higher-order vesicle assemblies has discipline-spanning potential from
responsive soft-matter materials to artificial cell networks in synthetic biology. This potential …

Building programmable multicompartment artificial cells incorporating remotely activated protein channels using microfluidics and acoustic levitation

J Li, WD Jamieson, P Dimitriou, W Xu, P Rohde… - Nature …, 2022 - nature.com
Intracellular compartments are functional units that support the metabolism within living
cells, through spatiotemporal regulation of chemical reactions and biological processes …

High-throughput optical sensing of nucleic acids in a nanopore array

S Huang, M Romero-Ruiz, OK Castell, H Bayley… - Nature …, 2015 - nature.com
Protein nanopores such as α-haemolysin and Mycobacterium smegmatis porin A (MspA)
can be used to sequence long strands of DNA at low cost. To provide high-speed …

Dynamic tuneable G protein-coupled receptor monomer-dimer populations

PM Dijkman, OK Castell, AD Goddard… - Nature …, 2018 - nature.com
G protein-coupled receptors (GPCRs) are the largest class of membrane receptors, playing
a key role in the regulation of processes as varied as neurotransmission and immune …

Constructing droplet interface bilayers from the contact of aqueous droplets in oil

S Leptihn, OK Castell, B Cronin, EH Lee, LCM Gross… - Nature protocols, 2013 - nature.com
We describe a protocol for forming an artificial lipid bilayer by contacting nanoliter aqueous
droplets in an oil solution in the presence of phospholipids. A lipid monolayer forms at each …

Functional aqueous droplet networks

MJ Booth, VR Schild, FG Downs, H Bayley - Molecular BioSystems, 2017 - pubs.rsc.org
Droplet interface bilayers (DIBs), comprising individual lipid bilayers between pairs of
aqueous droplets in an oil, are proving to be a useful tool for studying membrane proteins …

Adsorption kinetics dictate monolayer self-assembly for both lipid-in and lipid-out approaches to droplet interface bilayer formation

GA Venkatesan, J Lee, AB Farimani, M Heiranian… - Langmuir, 2015 - ACS Publications
The droplet interface bilayer (DIB) a method to assemble planar lipid bilayer membranes
between lipid-coated aqueous droplets has gained popularity among researchers in many …

Staphylococcus aureus α-toxin: small pore, large consequences

G von Hoven, Q Qin, C Neukirch, M Husmann… - Biological …, 2019 - degruyter.com
The small β-pore-forming α-toxin, also termed α-hemolysin or Hla is considered to be an
important virulence factor of Staphylococcus aureus. Perforation of the plasma membrane …