Polycyclic aromatic hydrocarbons and PAH-related DNA adducts
B Ewa, MŠ Danuta - Journal of applied genetics, 2017 - Springer
Investigations on the impact of chemicals on the environment and human health have led to
the development of an exposome concept. The exposome refers to the totality of exposures …
the development of an exposome concept. The exposome refers to the totality of exposures …
Joint American Academy of Dermatology–National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis in pediatric patients
A Menter, KM Cordoro, DMR Davis… - Journal of the American …, 2020 - Elsevier
Psoriasis is a chronic, multisystem, inflammatory disease that affects approximately 1% of
children, with onset most common during adolescence. This guideline addresses important …
children, with onset most common during adolescence. This guideline addresses important …
Molecular mechanisms linking environmental toxicants to cancer development: Significance for protective interventions with polyphenols
Human exposure to environmental toxicants with diverse mechanisms of action is a growing
concern. In addition to well-recognized carcinogens, various chemicals in environmental …
concern. In addition to well-recognized carcinogens, various chemicals in environmental …
Pediatric psoriasis: From new insights into pathogenesis to updates on treatment
HO Kim, SY Kang, JC Kim, CW Park, BY Chung - Biomedicines, 2021 - mdpi.com
Psoriasis is a chronic inflammatory systemic disease primarily affecting the skin, but which
often involves considerable comorbidities as well. One-third of psoriasis cases start during …
often involves considerable comorbidities as well. One-third of psoriasis cases start during …
Systemic inflammation, oxidative damage to nucleic acids, and metabolic syndrome in the pathogenesis of psoriasis
L Borska, J Kremlacek, C Andrys, J Krejsek… - International journal of …, 2017 - mdpi.com
In the pathogenesis of psoriasis, systemic inflammation and oxidative stress play mutual
roles interrelated with metabolic syndrome (MetS). This study aims to map the selected …
roles interrelated with metabolic syndrome (MetS). This study aims to map the selected …
[HTML][HTML] Association between United States Environmental Contaminants and the Prevalence of Psoriasis Derived from the National Health and Nutrition Examination …
L Guo, B Tu, D Li, L Zhi, Y Zhang, H Xiao, W Li, X Xu - Toxics, 2024 - mdpi.com
(1) Background: Prolonged coexposure to environmental contaminants is reportedly
associated with adverse impacts on skin health. However, the collective effects of …
associated with adverse impacts on skin health. However, the collective effects of …
Toxicokinetics of benzo [a] pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing
E Madeen, LK Siddens, S Uesugi, T McQuistan… - Toxicology and applied …, 2019 - Elsevier
Abstract Benzo [a] pyrene (BaP), is a known human carcinogen (International Agency for
Research on Cancer (IARC) class 1). The remarkable sensitivity (zepto-attomole 14 C in …
Research on Cancer (IARC) class 1). The remarkable sensitivity (zepto-attomole 14 C in …
Influence of dermal exposure to ultraviolet radiation and coal tar (polycyclic aromatic hydrocarbons) on the skin aging process
L Borska, C Andrys, J Krejsek, V Palicka… - Journal of …, 2016 - Elsevier
Background Ultraviolet radiation (UVR) and crude coal tar (CCT) containing PAHs can
accelerate the skin-aging process (SAP). However, UVR induces the formation of an …
accelerate the skin-aging process (SAP). However, UVR induces the formation of an …
Off-label treatments for pediatric psoriasis: lessons for the clinic
MB Haulrig, C Zachariae, L Skov - Psoriasis: Targets and Therapy, 2021 - Taylor & Francis
Psoriasis is a chronic inflammatory skin disease that affects up to 1.2% of children and
adolescents. The treatment options for childhood psoriasis are often based on the same …
adolescents. The treatment options for childhood psoriasis are often based on the same …
Genetic polymorphisms in biotransformation enzymes for benzo [a] pyrene and related levels of benzo [a] pyrene-7, 8-diol-9, 10-epoxide-DNA adducts in Goeckerman …
M Beranek, Z Fiala, J Kremlacek, C Andrys… - Toxicology Letters, 2016 - Elsevier
Goeckerman therapy (GT) for psoriasis combines the therapeutic effect of crude coal tar
(CCT) and ultraviolet radiation (UVR). CCT contains polycyclic aromatic hydrocarbons …
(CCT) and ultraviolet radiation (UVR). CCT contains polycyclic aromatic hydrocarbons …