Sirtuins, a promising target in slowing down the ageing process

W Grabowska, E Sikora, A Bielak-Zmijewska - Biogerontology, 2017 - Springer
Ageing is a plastic process and can be successfully modulated by some biomedical
approaches or pharmaceutics. In this manner it is possible to delay or even prevent some …

The crosstalk between the gut microbiota and mitochondria during exercise

A Clark, N Mach - Frontiers in physiology, 2017 - frontiersin.org
Many physiological changes occur in response to endurance exercise in order to adapt to
the increasing energy needs, mitochondria biogenesis, increased reactive oxygen species …

The impact of moderate-intensity continuous or high-intensity interval training on adipogenesis and browning of subcutaneous adipose tissue in obese male rats

M Khalafi, H Mohebbi, ME Symonds, P Karimi, A Akbari… - Nutrients, 2020 - mdpi.com
This study compares the effect of two types of exercise training, ie, moderate-intensity
continuous training (MICT) or high-intensity interval training (HIIT) on the browning of …

Sirtuin 1 in endothelial dysfunction and cardiovascular aging

S Ministrini, YM Puspitasari, G Beer, L Liberale… - Frontiers in …, 2021 - frontiersin.org
Sirtuin 1 (SIRT1) is a histone deacetylase belonging to the family of Sirtuins, a class of
nicotinamide adenine dinucleotide (NAD+)-dependent enzymes with multiple metabolic …

Key signaling pathways in aging and potential interventions for healthy aging

M Yu, H Zhang, B Wang, Y Zhang, X Zheng, B Shao… - Cells, 2021 - mdpi.com
Aging is a fundamental biological process accompanied by a general decline in tissue
function. Indeed, as the lifespan increases, age-related dysfunction, such as cognitive …

Satellite cells in ageing: use it or lose it

W Chen, D Datzkiw, MA Rudnicki - Open biology, 2020 - royalsocietypublishing.org
Individuals that maintain healthy skeletal tissue tend to live healthier, happier lives as proper
muscle function enables maintenance of independence and actuation of autonomy. The …

[HTML][HTML] The effect of eight weeks resistance and endurance training on some angiogenesis factors of hippocampus tissue in male wistar rats

M Sadegh Ghomi, M Kashef… - Journal of Sport and …, 2021 - joeppa.sbu.ac.ir
Purpose: One of the cause of adaptations due to exercise training is increased capillary
density or angiogenesis. increased blood flow to hippocampus tissue causes improvement …

مقایسة اثر تمرین تناوبی شدید و مقاومتی فزاینده بر بیان ژن ATF3 عضلة قلبی موش‌های صحرایی دیابتی نر

سفال منش, شهاب الدین, خالدی, ندا, رجبی… - نشریه فیزیولوژی ورزش و …, 2021‎ - joeppa.sbu.ac.ir
هدف: از سازوکارهای مؤثر در انجام بهتر عملکرد عضلانی در ورزشکاران، القای ظرفیت
پیش‌فعال‌سازی (PAP) در روش گرم کردن است. ازاین‌رو، پژوهش حاضر به‌منظور بررسی تأثیر گرم …

Effect of 12-weeks high-intensity interval training on SIRT1, PGC-1α and ERRα protein expression in aged rats

A Bakhtiyari, A Gaeni, S Chobineh… - Journal of Applied …, 2018 - jahssp.azaruniv.ac.ir
Exercise training improved impaired mitochondrial protein and enzymatic functional induced
aging. The purpose of this study was to investigate the effects of 12-weeks of high-intensity …

Pleiotropic and multi-systemic actions of physical exercise on PGC-1α signaling during the aging process

IV de Sousa Neto, AP Pinto, VR Muñoz… - Ageing research …, 2023 - Elsevier
Physical training is a potent therapeutic approach for improving mitochondrial health
through peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) …