This consensus document provides an up-to-date account of the various methods available
for the investigation of chronic venous insufficiency of the lower limbs (CVI), with an outline …

Microcirculation represents the smallest functional unit of the cardiovascular system, where
the interaction between blood and tissue creates the environment necessary for cell …

BACKGROUND: Deep vein thrombosis (DVT) is the formation of a blood clot within the deep
veins. During periods of sitting, blood flow is decreased and this contributes to an increased …

Objective To examine the historical development, evolution, strengths and weaknesses, and
applications (current and future) of laser Doppler flowmetry (LDF). Design A review and …

Purpose: Leg elevation is advised in the treatment of venous disease associated with
edema. We have used laser Doppler fluxmetry to assess the effects of leg elevation on the …

One hundred forty-seven consecutive patients with limb-threatening acute diabetic pedal
sepsis and/or chronic ischemia (Fontaine III/IV) were prospectively studied. Forty-four with …

In this review, the anatomy and physiology of the venous system and its pathophysiology are
described. Theories regarding the possible causes of disturbances in venous …

Venous disease is the most common cause of chronic leg ulceration and represents an
advanced clinical manifestation of venous insufficiency. Due to their frequency and …

Purpose: The reasons for the efficacy of leg compression in the treatment of chronic venous
insufficiency are not clear. We have used laser Doppler fluxmetry to assess the effect of …

Chronic wounds, in particular venous leg ulcers (VLU), represent a substantial burden for
economies, healthcare systems and societies worldwide. This burden is exacerbated by the …