Historically, natural plant-derived drugs received a great impact of consideration in the
treatment of several human-associated disorders. Cancer is a devastating disease and the …

Drug repurposing (or repositioning) is an emerging concept to use old drugs for new
treatment indications. Phytochemicals isolated from medicinal plants have been largely …

Benzophenanthridine alkaloids are a class of isoquinoline compounds, which are widely
found in the plants of papaveraceae, corydalis, and rutaceae. Biological activities and …

Historically, natural products have represented a significant source of anticancer agents,
with plant-derived drugs becoming increasingly explored. In particular, sanguinarine is a …

Sanguinarine is a best-known member of a relatively small group of quaternary benzo [c]
phenanthridine alkaloids (QBAs). QBAs are widely distributed in the family Papaveraceae …

In vitro and in vivo studies have revealed that Sanguinarine has antioxidant, anti-
inflammatory, proapoptotic, and growth inhibitory effects on tumor cells of a variety of …

Angiogenesis is a process that drives breast cancer (BC) progression and metastasis, which
is linked to the altered inflammatory process, particularly in triple-negative breast cancer …

Schistosomiasis, a snail-borne parasitic disease, affects more than 200 million people
worldwide. Currently the treatment of schistosomiasis relies on a single therapy of …

Sanguinarine (Sang)–a benzophenanthridine alkaloid extracted from Sanguinaria
canadensis–exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory …

Basal-like breast cancer (BLBC) remains a great challenge because of its clinically
aggressive nature and lack of effective targeted therapy. We analyzed the potential anti …