Temporal control is central to deploy and coordinate genetic programs during development.
At present, there is limited understanding of the molecular mechanisms that govern the …

Simple Summary Large organisms are not simply proportionately magnified versions of
smaller related organisms. The magnitude of various features of organisms often changes …

Highlights•The speed of gene expression steps correlates with the rate of embryonic
development.•Mitochondrial metabolism may give rise to species-specific gene expression …

During embryonic development, the timing of events at the cellular level must be
coordinated across multiple length scales to ensure the formation of a well-proportioned …

Living systems have some of the most sophisticated reaction circuits in the world, realizing
many incredibly complex functions through a variety of simple molecular reactions, in which …

During embryonic development, the timing of events at the cellular level must be
coordinated across multiple length scales to ensure the formation of a well-proportioned …

The speed of embryonic development varies considerably between mammalian species, yet
the underlying molecular mechanisms remain poorly understood. To investigate the basis …

Embryo development is a dynamic process governed by the regulation of timing and
sequences of gene expression, which control the proper growth of the organism. While …

Understanding the temporal dynamics of T-cell transcription is crucial for insights into
immune cell function and development. In this study, we show the features of the Timer-of …

Biliary atresia (BA) is a cholangiopathy affecting the extrahepatic bile duct (EHBD) of
newborns. The etiology and pathophysiology of BA are not fully understood; however …