The circadian clock system consists of a central clock located in the suprachiasmatic
nucleus in the hypothalamus and peripheral clocks in peripheral tissues. Peripheral clocks …

The circadian clock controls several aspects of mammalian physiology and orchestrates the
daily oscillations of biological processes and behavior. Our circadian rhythms are driven by …

Living beings spend their lives and carry out their daily activities interacting with
environmental situations that present space-time variations and that involve contact with …

Hepatic encephalopathy (HE) is a common, incapacitating complication of cirrhosis that
affects many patients with cirrhosis. Although several therapies have proven effective in the …

Simple Summary The circadian coordination of metabolism is tightly regulated, and its
alteration can trigger several diseases, including liver steatohepatitis and cancer. Many …

The circadian clock underpins most physiological conditions and provides a temporal
dimension to our understanding of body and tissue homeostasis. Disruptions of circadian …

Circadian rhythms are intrinsic 24-hour oscillations found in nearly all life forms. They
orchestrate key physiological and behavioral processes, allowing anticipation and response …

Infection with hepatitis B virus (HBV) is a major risk factor for hepatocellular carcinoma
(HCC) in developed countries. Epidemiological reports indicate that the incidence of HBV …

Chronic hepatitis B virus (HBV) infection is a major cause of liver disease and cancer
worldwide for which there are no curative therapies. The major challenge in curing infection …

Circadian rhythms are present in almost every organism and regulate multiple aspects of
biological and physiological processes (eg metabolism, immune responses, and microbial …