Finding the target sites of RNA‐binding proteins
X Li, H Kazan, HD Lipshitz… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
RNA–protein interactions differ from DNA–protein interactions because of the central role of
RNA secondary structure. Some RNA‐binding domains (RBDs) recognize their target sites …
RNA secondary structure. Some RNA‐binding domains (RBDs) recognize their target sites …
From cis-regulatory elements to complex RNPs and back
Messenger RNAs (mRNAs), the templates for translation, have evolved to harbor abundant
cis-acting sequences that affect their posttranscriptional fates. These elements are frequently …
cis-acting sequences that affect their posttranscriptional fates. These elements are frequently …
[HTML][HTML] A non-amyloid prion particle that activates a heritable gene expression program
AK Chakravarty, T Smejkal, AK Itakura, DM Garcia… - Molecular cell, 2020 - cell.com
Spatiotemporal gene regulation is often driven by RNA-binding proteins that harbor long
intrinsically disordered regions in addition to folded RNA-binding domains. We report that …
intrinsically disordered regions in addition to folded RNA-binding domains. We report that …
Structural basis for binding of Drosophila Smaug to the GPCR Smoothened and to the germline inducer Oskar
J Kubíková, G Ubartaitė, J Metz… - Proceedings of the …, 2023 - National Acad Sciences
Drosophila Smaug and its orthologs comprise a family of mRNA repressor proteins that
exhibit various functions during animal development. Smaug proteins contain a …
exhibit various functions during animal development. Smaug proteins contain a …
Multiple Upstream Signals Converge on the Adaptor Protein Mst50 in Magnaporthe grisea
Rice blast fungus (Magnaporthe grisea) forms a highly specialized infection structure for
plant penetration, the appressorium, the formation and growth of which are regulated by the …
plant penetration, the appressorium, the formation and growth of which are regulated by the …
The transmembrane protein FgSho1 regulates fungal development and pathogenicity via the MAPK module Ste50‐Ste11‐Ste7 in Fusarium graminearum
Q Gu, Y Chen, Y Liu, C Zhang, Z Ma - New Phytologist, 2015 - Wiley Online Library
The mitogen‐activated protein kinase (MAPK) signaling pathways have been characterized
in Fusarium graminearum. Currently, the upstream sensors of these pathways are unknown …
in Fusarium graminearum. Currently, the upstream sensors of these pathways are unknown …
Viral hijacking of the TENT4–ZCCHC14 complex protects viral RNAs via mixed tailing
D Kim, Y Lee, SJ Jung, J Yeo, JJ Seo, YY Lee… - Nature Structural & …, 2020 - nature.com
TENT4 enzymes generate 'mixed tails' of diverse nucleotides at 3′ ends of RNAs via
nontemplated nucleotide addition to protect messenger RNAs from deadenylation. Here we …
nontemplated nucleotide addition to protect messenger RNAs from deadenylation. Here we …
Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression
J Chicoine, P Benoit, C Gamberi, M Paliouras… - Developmental cell, 2007 - cell.com
Summary Bicaudal-C (Bic-C) encodes an RNA-binding protein required maternally for
patterning the Drosophila embryo. We identified a set of mRNAs that associate with Bic-C in …
patterning the Drosophila embryo. We identified a set of mRNAs that associate with Bic-C in …
Global regulation of mRNA translation and stability in the early Drosophilaembryo by the Smaug RNA-binding protein
L Chen, JG Dumelie, X Li, MHK Cheng, Z Yang… - Genome biology, 2014 - Springer
Background Smaug is an RNA-binding protein that induces the degradation and represses
the translation of mRNAs in the early Drosophila embryo. Smaug has two identified direct …
the translation of mRNAs in the early Drosophila embryo. Smaug has two identified direct …
The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG
E Kugler, S Madiwale, D Yong, JAI Thoms… - Nature …, 2023 - nature.com
The ERG (ETS-related gene) transcription factor is linked to various types of cancer,
including leukemia. However, the specific ERG domains and co-factors contributing to …
including leukemia. However, the specific ERG domains and co-factors contributing to …