Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs

W Liu, R Gust - Coordination Chemistry Reviews, 2016 - Elsevier
The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

Perspectives of benzimidazole derivatives as anticancer agents in the new era

S Yadav, B Narasimhan - Anti-Cancer Agents in Medicinal …, 2016 - ingentaconnect.com
Cancer is one of the deadliest diseases nowadays and is a great topic for research as the
challenging task is to develop new entities with selectivity towards cancerous cells …

Human colon cancer targeted pro-apoptotic, anti-metastatic and cytostatic effects of binuclear Silver (I)–N-Heterocyclic carbene (NHC) complexes

M Asif, MA Iqbal, MA Hussein, CE Oon… - European journal of …, 2016 - Elsevier
The current mechanistic study was conducted to explore the effects of increased lipophilicity
of binuclear silver (I)–NHC complexes on cytotoxicity. Two new silver (I)–N-Heterocyclic …

[HTML][HTML] Potential of silver against human colon cancer: (synthesis, characterization and crystal structures of xylyl (Ortho, meta, & Para) linked bis-benzimidazolium salts and …

MA Iqbal, RA Haque, SF Nasri, AMSA Majid… - Chemistry Central …, 2013 - Springer
Background Since the first successful synthesis of Ag (I)-N-heterocyclic carbene complex in
1993, this class of compounds has been extensively used for transmetallation reactions …

Novel N-heterocyclic carbene silver (I) complexes: Synthesis, structural characterization, and anticancer activity

S Şahin-Bölükbaşı, N Şahin, MN Tahir, C Arıcı… - Inorganica Chimica …, 2019 - Elsevier
In this study, we synthesized four novel unsymmetrically substituted NHC ligands (1a-d) and
their Ag (I) complexes (2a-d). All new compounds were characterized using elemental …

Synthesis and anticancer activity of para-xylyl linked bis-benzimidazolium salts and respective Ag(I) N-heterocyclic carbene complexes

MA Iqbal, RA Haque, MBK Ahamed… - Medicinal Chemistry …, 2013 - Springer
The article describes synthesis, characterization (NMR, FT-IR, microanalysis, X-ray
crystallography), and in vitro anticancer activity of para-xylyl linked bis-benzimidazolium …

Development of a fluorescent chemosensor for chloride ion detection in sweat using Ag+-benzimidazole complexes

J Kim, S Lee, S Kim, M Jung, H Lee, MS Han - Dyes and Pigments, 2020 - Elsevier
The level of chloride ions (Cl⁻) in sweat is a recognized biomarker for the genetic disorder
cystic fibrosis (CF). The accurate quantitation of chloride ions in sweat is therefore a vital …

Macrophage and colon tumor cells as targets for a binuclear silver (I) N-heterocyclic carbene complex, an anti-inflammatory and apoptosis mediator

MA Iqbal, MI Umar, RA Haque, MBK Ahamed… - Journal of inorganic …, 2015 - Elsevier
Chronic inflammation intensifies the risk for malignant neoplasm, indicating that curbing
inflammation could be a valid strategy to prevent or cure cancer. Cancer and inflammation …

Synthesis and biological evaluation of substituted N-(2-(1H-benzo [d] imidazol-2-yl) phenyl) cinnamides as tubulin polymerization inhibitors

K Donthiboina, P Anchi, S Gurram, GS Mani… - Bioorganic …, 2020 - Elsevier
A new series of N-(2-(1H-benzo [d] imidazol-2-yl) phenyl) cinnamides was prepared and
evaluated for their in vitro cytotoxic activity using various cancer cell lines viz. A549 (human …

Synthesis, structure, anticancer, and antioxidant activity of para-xylyl linked bis-benzimidazolium salts and respective dinuclear Ag(I) N-heterocyclic carbene …

RA Haque, MA Iqbal, P Asekunowo… - Medicinal Chemistry …, 2013 - Springer
The article describes synthesis, characterization (NMR, FT-IR, microanalysis, X-ray
crystallography), in vitro anticancer, and antioxidant activity of para-xylyl linked bis …