Stemness combines the ability of a cell to perpetuate its lineage, to give rise to differentiated
cells, and to interact with its environment to maintain a balance between quiescence …

The accumulation of adipose tissue in the body occurs because the energy introduced with
food and drink exceeds that expense, but to understand why this imbalance is established …

Over the years, researchers tried to explain cancer pathogenesis by taking into
consideration different factors, such as immune system, the genetic predisposition and …

Cholangiocarcinoma (CCA) is the second most common type of liver cancer, and is highly
aggressive with very poor prognosis. CCA is classified into intrahepatic cholangiocarcinoma …

Several factors, such as ischemia, infection and skin injury impair the wound healing
process. One common pathway in all these processes is related to the reactive oxygen …

Inflammatory bowel diseases (IBD) are associated with an increased risk of colitis-
associated colorectal carcinoma (CAC). CAC is one of the most important causes of …

Oral cancers have been proven to arise from precursors lesions and to be related to risk
behaviour such as alcohol consumption and smoke. However, the present paper focuses on …

The tumour suppressor gene F‑box and WD repeat domain‑containing 7 (FBXW7) plays an
important role in human cancer by regulating cell division, proliferation and differentiation …

Giulio Bizzozero classified the tissues concerning their capacity to self-renew during the
adult life in labile, stable and permanent tissues. In 1940 Viktor Hamburger and Rita Levi …

At present, after extensive studies in the field of cancer, cancer stem cells (CSCs) have been
proposed as a major factor in tumor initiation, progression, metastasis, and recurrence …