[HTML][HTML] Salmonella Pathogenicity Island 1 (SPI-1) and Its Complex Regulatory Network

L Lou, P Zhang, R Piao, Y Wang - Frontiers in cellular and infection …, 2019 - frontiersin.org
Salmonella species can infect a diverse range of birds, reptiles, and mammals, including
humans. The type III protein secretion system (T3SS) encoded by Salmonella pathogenicity …

The type III secretion system needle, tip, and translocon

S Dey, A Chakravarty, P Guha Biswas… - Protein …, 2019 - Wiley Online Library
Many Gram‐negative bacteria pathogenic to plants and animals deploy the type III secretion
system (T3SS) to inject virulence factors into their hosts. All bacteria that rely on the T3SS to …

[HTML][HTML] Molecular targets and strategies for inhibition of the bacterial type III secretion system (T3SS); inhibitors directly binding to T3SS components

JA Hotinger, HA Pendergrass, AE May - Biomolecules, 2021 - mdpi.com
The type III secretion system (T3SS) is a virulence apparatus used by many Gram-negative
pathogenic bacteria to cause infections. Pathogens utilizing a T3SS are responsible for …

An elegant nano-injection machinery for sabotaging the host: Role of Type III secretion system in virulence of different human and animal pathogenic bacteria

D Hajra, AV Nair, D Chakravortty - Physics of life Reviews, 2021 - Elsevier
Various Gram-negative bacteria possess a specialized membrane-bound protein secretion
system known as the Type III secretion system (T3SS), which transports the bacterial effector …

Infection biology of Salmonella enterica

J Han, N Aljahdali, S Zhao, H Tang, H Harbottle… - EcoSal …, 2024 - Am Soc Microbiol
Salmonella enterica is the leading cause of bacterial foodborne illness in the USA, with an
estimated 95% of salmonellosis cases due to the consumption of contaminated food …

Type 3 secretion system 1 of Salmonella typhimurium and its inhibitors: a novel strategy to combat salmonellosis

S Hussain, P Ouyang, Y Zhu, A Khalique, C He… - … Science and Pollution …, 2021 - Springer
Unsuccessful vaccination against Salmonella due to a large number of serovars, and
antibiotic resistance, necessitates the development of novel therapeutics to treat …

The structure of the type III secretion system needle complex

S Miletic, N Goessweiner-Mohr, TC Marlovits - Bacterial Type III Protein …, 2020 - Springer
The type III secretion system (T3SS) is an essential virulence factor of many pathogenic
bacterial species including Salmonella, Yersinia, Shigella and enteropathogenic …

[HTML][HTML] Single-domain antibodies pinpoint potential targets within Shigella invasion plasmid antigen D of the needle tip complex for inhibition of type III secretion

ML Barta, JP Shearer, O Arizmendi… - Journal of Biological …, 2017 - ASBMB
Numerous Gram-negative pathogens infect eukaryotes and use the type III secretion system
(T3SS) to deliver effector proteins into host cells. One important T3SS feature is an …

Characterization of Small‐Molecule Scaffolds That Bind to the Shigella Type III Secretion System Protein IpaD

S Dey, A Anbanandam, BE Mumford… - …, 2017 - Wiley Online Library
Many pathogens such as Shigella and other bacteria assemble the type III secretion system
(T3SS) nanoinjector to inject virulence proteins into their target cells to cause infectious …

Detergent isolation stabilizes and activates the Shigella type III secretion system translocator protein IpaC

AR Bernard, SM Duarte, P Kumar… - Journal of pharmaceutical …, 2016 - Elsevier
Shigella rely on a type III secretion system as the primary virulence factor for invasion and
colonization of human hosts. Although there are an estimated 90 million Shigella infections …