High-throughput next-generation sequencing now makes it possible to generate a vast
amount of multi-omics data for various applications. These data have revolutionized …

Breast cancer, the most common type of cancer affecting women, encompasses a collection
of histologic (mainly ductal and lobular) and molecular subtypes exhibiting diverse clinical …

Mass cytometry enables high-dimensional, single-cell analysis of cell type and state. In
mass cytometry, rare earth metals are used as reporters on antibodies. Analysis of metal …

The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Background Breast cancer cell lines have been used widely to investigate breast cancer
pathobiology and new therapies. Breast cancer is a molecularly heterogeneous disease …

In the last decade, the development of microarrays and the ability to perform massively
parallel gene expression analysis of human tumours were received with great excitement by …

The study of organs and tissues on a molecular level is necessary as we seek an
understanding of health and disease. Over the last few years, powerful highly multiplexed …

Triple-negative breast cancers (TNBC), characterized by absence of estrogen receptor (ER),
progesterone receptor (PR) and lack of overexpression of human epidermal growth factor …

Among many nanoparticle-based delivery platforms, liposomes have been particularly
successful with many formulations passed into clinical applications. They are well …

Background We hypothesized that distinct biological processes might be associated with
prognosis and chemotherapy sensitivity in the different types of breast cancers. Methods We …