In recent years, tremendous progress has been made in understanding the mechanisms
underlying the specification of projection neurons within the mammalian neocortex. New …

The cerebral cortex of the human brain is a sheet of about 10 billion neurons divided into
discrete subdivisions or areas that process particular aspects of sensation, movement, and …

Idiopathic autism spectrum disorder (ASD) is highly heterogeneous, and it remains unclear
how convergent biological processes in affected individuals may give rise to symptoms …

Human induced pluripotent stem cells (hiPSCs) are emerging as a tool for understanding
human brain development at cellular, molecular, and genomic levels. Here we show that …

In the developing cerebral cortex, neurons are born on a predictable schedule. Here we
show in mice that the essential timing mechanism is programmed within individual …

Microglia are observed in the early developing forebrain and contribute to the regulation of
neurogenesis through still unravelled mechanisms. In the developing cerebral cortex …

microRNA-9-2 and microRNA-9-3 double-mutant mice demonstrate that microRNA-9 (miR-
9) controls neural progenitor proliferation and differentiation in the developing …

GABAergic dysfunction is present in the hippocampus in schizophrenia (SZ) and bipolar
disorder (BD). The trisynaptic pathway was “deconstructed” into various layers of sectors …

The immense range of human behaviours is rooted in the complex neural networks of the
cerebrum. The creation of these networks depends on the precise integration of specific …

Cranial placodes are specialized regions of the ectoderm, which give rise to various sensory
ganglia and contribute to the pituitary gland and sensory organs of the vertebrate head …