Optical imaging in disease diagnosis and treatment benefits from high spatiotemporal
resolution and the availability of numerous optical agents. However, many optical imaging …

Despite advancements in standardizing the criteria for acute kidney injury (AKI), its definition
remains based on changes in serum creatinine and urinary output that do not specifically …

Drug-induced acute kidney injury (AKI) with a high morbidity and mortality is poorly
diagnosed in hospitals and deficiently evaluated in drug discovery. Here, we report the …

Acute kidney injury (AKI) is a prevalent and lethal adverse event that severely affects cancer
patients receiving chemotherapy. It is correlated with the collateral damage to renal cells …

Kidney cells and tissues derived from human pluripotent stem cells (hPSCs) may enable
organ regeneration, disease modeling and drug screening. We report an efficient …

Background: Worsening renal function (WRF) in the setting of aggressive diuresis for acute
heart failure treatment may reflect renal tubular injury or simply indicate a hemodynamic or …

Various biomarkers of acute kidney injury (AKI) have been discovered and characterized in
the recent past. These molecules can be detected in urine or blood and signify structural …

Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here,
we review the major components of this dynamic process, which involves hemodynamic …

Blood urea nitrogen and serum creatinine are imperfect markers of kidney function because
they are influenced by many renal and nonrenal factors independent of kidney function. A …

Acute kidney injury (AKI) is a common complication of critical illnesses and has a significant
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …