Ageing is a complex biological process in which a gradual decline in physiological fitness
increases susceptibility to diseases such as neurodegenerative disorders and cancer …

During the aging process or disease progression, normal cells and tissues in the body
undergo various stresses, leading to cell damage and the need for repair, adaptation …

Senescent cells accumulate throughout the body with advanced age, diseases and chronic
conditions. They negatively impact health and function of multiple systems, including the …

The intricate interplay between cellular senescence and alterations in the gut microbiome
emerges as a pivotal axis in the aging process, increasingly recognized for its contribution to …

Advancing age is associated with several age-related diseases (ARDs), with
musculoskeletal conditions impacting millions of elderly people worldwide. With orthopedic …

PARPi is currently the most important breakthrough in the treatment of ovarian cancer in
decades, and it has been integrated into the initial maintenance therapy for ovarian cancer …

Aging and circadian rhythms have been connected for decades, but their molecular
interaction has remained unknown, especially for cancers. In this situation, we summarized …

Periodontitis is a multifactorial chronic inflammatory disease that destroy periodontium. Apart
from microbial infection and host immune responses, emerging evidence shows aging and …

Beta (β)-cell senescence contributes to type 2 diabetes mellitus (T2DM). While exercise is
vital for T2DM management and significantly affects cellular ageing markers, its effect on β …

Life stress can shorten lifespan and increase risk for aging-related diseases, but the biology
underlying this phenomenon remains unclear. Here we assessed the effect of chronic stress …