Physicochemical characteristics of droplet interface bilayers
Droplet interface bilayer (DIB) is a lipid bilayer formed when two lipid monolayer-coated
aqueous droplets are brought in contact within an oil phase. DIBs, especially post …
aqueous droplets are brought in contact within an oil phase. DIBs, especially post …
Peptide‐based coacervate‐core vesicles with semipermeable membranes
M Abbas, JO Law, SN Grellscheid… - Advanced …, 2022 - Wiley Online Library
Coacervates droplets have long been considered as potential protocells to mimic living
cells. However, these droplets lack a membrane and are prone to coalescence, limiting their …
cells. However, these droplets lack a membrane and are prone to coalescence, limiting their …
Challenges and opportunities in achieving the full potential of droplet interface bilayers
Abstract Model membranes can be used to elucidate the intricacies of the chemical
processes that occur in cell membranes, but the perfectly biomimetic, yet bespoke, model …
processes that occur in cell membranes, but the perfectly biomimetic, yet bespoke, model …
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity
M de Jesus, AH Settle, D Vorselen, TK Gaetjens… - Science …, 2024 - science.org
Immune cells have intensely physical lifestyles characterized by structural plasticity and
force exertion. To investigate whether specific immune functions require stereotyped …
force exertion. To investigate whether specific immune functions require stereotyped …
Characterization and associated pressure-dependent behavior of deposits formed during sterile filtration of mRNA-Lipid nanoparticles
The recent success of mRNA vaccines has generated increased interest in the use of Lipid
Nanoparticles (LNPs) for delivery of nucleic acids. The objective of this study was to …
Nanoparticles (LNPs) for delivery of nucleic acids. The objective of this study was to …
Entrapment and voltage-driven reorganization of hydrophobic nanoparticles in planar phospholipid bilayers
Engineered nanoparticles (NPs) possess diverse physical and chemical properties, which
make them attractive agents for targeted cellular interactions within the human body. Once …
make them attractive agents for targeted cellular interactions within the human body. Once …
Simultaneous Electrophysiology and Imaging Reveal Changes in Lipid Membrane Thickness and Tension upon Uptake of Amphiphilic Gold Nanoparticles
Amphiphilic gold core nanoparticles (AmNPs) striped with hydrophilic 11-mercapto-1-
undecanesulfonate (MUS) and hydrophobic 1-octanethiol (OT) ligands are promising …
undecanesulfonate (MUS) and hydrophobic 1-octanethiol (OT) ligands are promising …
Characterizing the structure and interactions of model lipid membranes using electrophysiology
J El-Beyrouthy, E Freeman - Membranes, 2021 - mdpi.com
The cell membrane is a protective barrier whose configuration determines the exchange
both between intracellular and extracellular regions and within the cell itself. Consequently …
both between intracellular and extracellular regions and within the cell itself. Consequently …
Droplet-based membranous soft materials
MM Makhoul-Mansour, EC Freeman - Langmuir, 2021 - ACS Publications
Inspired by the structure and functionality of natural cellular tissues, droplet interface bilayer
(DIB)-based materials strategically combine model membrane assembly techniques and …
(DIB)-based materials strategically combine model membrane assembly techniques and …
Programmable Lipid Bilayer Tension–Control Apparatus for Quantitative Mechanobiology
Y Matsuki, M Iwamoto, T Maki, M Takashima… - ACS …, 2024 - ACS Publications
The biological membrane is not just a platform for information processing but also a field of
mechanics. The lipid bilayer that constitutes the membrane is an elastic body, generating …
mechanics. The lipid bilayer that constitutes the membrane is an elastic body, generating …