An increasing recognition that brain and body are dynamically coupled has enriched our
scientific understanding of mental health conditions. Peripheral signals interact centrally to …

Background Psychological treatments occupy an important place in evidence-based mental
health treatments. Now is an exciting time to fuel treatment research: a pressing demand for …

We conducted genome-wide association analyses of over 250,000 participants of European
(EUR) and African (AFR) ancestry from the Million Veteran Program using electronic health …

Through advances in both basic and clinical scientific research, Pavlovian fear conditioning
and extinction have become an exemplary translational model for understanding and …

Angiotensin II receptor blockers (ARBs, collectively called sartans) are widely used
compounds therapeutically effective in cardiovascular disorders, renal disease, the …

The historically understood role of the central amygdala (CeA) in fear learning is to serve as
a passive output station for processing and plasticity that occurs elsewhere in the brain …

Posttraumatic stress disorder (PTSD) is a heterogeneous psychiatric disorder that affects
individuals exposed to trauma and is highly co-morbid with other adverse health outcomes …

Stress-and anxiety-related disorders are on the rise in both military and general populations.
Over the next decade, it is predicted that treatment of these conditions, in particular …

Posttraumatic stress disorder (PTSD) has long been associated with a heightened risk of
cardiovascular disease (CVD). A number of mechanisms have been implicated to underlie …

Although the fear response is an adaptive response to threatening situations, a number of
psychiatric disorders feature prominent fear-related symptoms caused, in part, by failures of …