Liquid chromatography (LC) is a separation technique used in many different areas to aid
the identification and quantification of substances in various matrices. LC techniques with …

Recently, a fixed dose combination (FDC) of memantine (MM) and donepezil (DPZ) has
been approved for the treatment of Alzheimer's disease (AD). In the present work, a liquid …

An overview of the state-of-the art in HPLC coupled with fluorescence detection is
presented. Over the last 20 years, the increasing number of methodological papers on this …

Memantine is a non‐competitive N‐methyl‐D‐aspartate (NMDA) receptor antagonist used to
treat Alzheimer's disease. We investigated memantine pharmacokinetics after oral, IV and …

A selective, new, rapid and nondestructive Fourier transform Infrared spectroscopic assay
has been developed for simultaneous determination of Memantine hydrochloride and …

Memantine is chemically a tricyclic amine and is used for Parkinson's disease and
movement disorders. Although several HPLC methods with different derivatization reagents …

Memantine, a non-competitive NMDA receptor antagonist, is used to treat Alzheimer's
disease. Therefore, loading memantine in nanoparticles (NPs) could be an essential tool to …

A rapid procedure for the determination of memantine based on hydrophilic interaction
chromatography with fluorescence detection was developed. Fluorescence detection after …

Potentiometric ion selective electrodes with simple design and high potential stability are
required for in-line process, clinical and quality control analysis. The objective of this work is …

This investigation describes a new precise, sensitive and accurate RP-HPLC method for the
Simultaneous estimation of Donepezil and Memantine in Bulk and Tablets. The resolution of …