Toxicity of metal–organic framework nanoparticles: from essential analyses to potential applications

R Ettlinger, U Lächelt, R Gref, P Horcajada… - Chemical Society …, 2022 - pubs.rsc.org
In the last two decades, the field of metal–organic frameworks (MOFs) has exploded, and
MOF nanoparticles in particular are being investigated with increasing interest for various …

[HTML][HTML] Metal-organic frameworks for advanced drug delivery

S He, L Wu, X Li, H Sun, T Xiong, J Liu, C Huang… - … Pharmaceutica Sinica B, 2021 - Elsevier
Abstract Metal-organic frameworks (MOFs), comprised of organic ligands and metal
ions/metal clusters via coordinative bonds are highly porous, crystalline materials. Their …

Application of zirconium MOFs in drug delivery and biomedicine

IA Lazaro, RS Forgan - Coordination chemistry reviews, 2019 - Elsevier
Nanoparticulate metal-organic frameworks (MOFs) have the requisite high storage
capacities, tailorable structures, ease of functionalisation, and excellent biocompatibilities for …

Multivariate modulation of the Zr MOF UiO‐66 for defect‐controlled combination anticancer drug delivery

I Abánades Lázaro, CJR Wells… - Angewandte Chemie, 2020 - Wiley Online Library
Metal–organic frameworks (MOFs) are emerging as leading candidates for nanoscale drug
delivery, as a consequence of their high drug capacities, ease of functionality, and the ability …

Metal–organic framework technologies for water remediation: towards a sustainable ecosystem

M Mon, R Bruno, J Ferrando-Soria… - Journal of materials …, 2018 - pubs.rsc.org
Having access to clean water is a mandatory requirement for the proper development of
living beings. So, addressing the removal of contaminants from aquatic systems should be a …

Nanostructured metal–organic frameworks and their bio-related applications

M Giménez-Marqués, T Hidalgo, C Serre… - Coordination Chemistry …, 2016 - Elsevier
Miniaturization of metal–organic frameworks (MOFs) results of great interest in order to
integrate these materials in strategic applications such as sensing or drug delivery. This …

[HTML][HTML] Size control over metal–organic framework porous nanocrystals

CR Marshall, SA Staudhammer, CK Brozek - Chemical science, 2019 - pubs.rsc.org
Porous nanocrystals of metal–organic frameworks (MOFs) offer greater bioavailability,
higher surface-to-volume ratios, superior control over MOF membrane fabrication, and …

[HTML][HTML] Selective surface PEGylation of UiO-66 nanoparticles for enhanced stability, cell uptake, and pH-responsive drug delivery

IA Lázaro, S Haddad, S Sacca, C Orellana-Tavra… - Chem, 2017 - cell.com
The high storage capacities and excellent biocompatibilities of metal-organic frameworks
(MOFs) have made them emerging candidates as drug-delivery vectors. Incorporation of …

[HTML][HTML] Degradation of ZIF-8 in phosphate buffered saline media

MJ Velásquez-Hernández, R Ricco, F Carraro… - …, 2019 - pubs.rsc.org
Understanding the stability of zeolitic imidazolate framework-8 (ZIF-8) under physiological
conditions is critical in biotechnology and biomedicine for biosensing, biocatalysis, and drug …

Metal–organic framework‐based nanomedicine platforms for drug delivery and molecular imaging

W Cai, CC Chu, G Liu, YXJ Wáng - Small, 2015 - Wiley Online Library
Metal–organic frameworks (MOFs), which are a unique class of hybrid porous materials built
from metal ions and organic linkers, have attracted significant research interest in recent …