Overview of monoamine transporters

S Aggarwal, OV Mortensen - Current protocols in …, 2017 - Wiley Online Library
Abstract The dopamine (DAT), serotonin (SERT), and norepinephrine (NET) transporters,
which are collectively referred to as monoamine transporters (MATs), play significant roles in …

Trace amine-associated receptor 1: a multimodal therapeutic target for neuropsychiatric diseases

MD Schwartz, JJ Canales, R Zucchi… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: The trace amines, endogenous amines closely related to the biogenic amine
neurotransmitters, have been known to exert physiological and neurological effects for …

The Multilayer Connectome of Caenorhabditis elegans

B Bentley, R Branicky, CL Barnes… - PLoS computational …, 2016 - journals.plos.org
Connectomics has focused primarily on the mapping of synaptic links in the brain; yet it is
well established that extrasynaptic volume transmission, especially via monoamines and …

The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus

NM Puri, GR Romano, TY Lin, QN Mai, R Irannejad - Elife, 2022 - elifesciences.org
Dopamine is a key catecholamine in the brain and kidney, where it is involved in a number
of physiological functions such as locomotion, cognition, emotion, endocrine regulation, and …

Potentiating SLC transporter activity: Emerging drug discovery opportunities

ML Rives, JA Javitch, AD Wickenden - Biochemical pharmacology, 2017 - Elsevier
Maintaining the integrity of cellular membranes is critical to protecting metabolic activities
and genetic information from the environment. Regulation of transport across membranes of …

Overlap and Specificity in the Substrate Spectra of Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3

L Gebauer, O Jensen, M Neif, J Brockmöller… - International Journal of …, 2021 - mdpi.com
Human monoamine transporters (MATs) are cation transporters critically involved in
neuronal signal transmission. While inhibitors of MATs have been intensively studied, their …

Bioelectrical control of positional information in development and regeneration: a review of conceptual and computational advances

A Pietak, M Levin - Progress in biophysics and molecular biology, 2018 - Elsevier
Positional information describes pre-patterns of morphogenetic substances that alter spatio-
temporal gene expression to instruct development of growth and form. A wealth of recent …

The influence of genetic variants on striatal dopamine transporter and D2 receptor binding after TB

AK Wagner, JM Scanion, CR Becker… - Journal of Cerebral …, 2014 - journals.sagepub.com
Dopamine (DA) neurotransmission influences cognition and recovery after traumatic brain
injury (TBI). We explored whether functional genetic variants affecting the DA transporter …

Prescription psychostimulants for cocaine use disorder: A review from molecular basis to clinical approach

VS Tardelli, LF Berro, G Gerra, L Tadonio… - Addiction …, 2023 - Wiley Online Library
Cocaine use is a public health concern in many countries worldwide, particularly in the
Americas and Oceania. Overdose deaths involving stimulants, such as cocaine, have been …

Monoamine transporter inhibitors and substrates as treatments for stimulant abuse

LL Howell, SS Negus - Advances in Pharmacology, 2014 - Elsevier
The acute and chronic effects of abused psychostimulants on monoamine transporters and
associated neurobiology have encouraged development of candidate medications that …